Bellver Capella Vicente
Universitat de Valància España.
Cuad Bioet. 2016 May-Aug;27(90):223-39.
After discovering the CRISPR-Cas9 as an extraordinary method for Gene editing it is necessary to reflect on the ethical, political and legal impact of this technology. This work pretends to offer a preliminary consideration of these problems. I do not pay attention to the potential of CRISPR-Cas9 in the fields of health or environment, nor to all the ethical, legal and political challenges it involves. I principally focus the attention on the possibility of using CRISPR-Cas9 to alter the human germ line. There are some rulings on this topic delivered by intergovernmental organizations. There also are some statements from the scientific community on the matter. They are important in order to know the reasons why they propose a moratorium on the use of CRISPR-Cas9 for human germ line editing. I begin the paper with a short explanation on how CRISPR-Cas9 works.
在发现CRISPR-Cas9作为一种非凡的基因编辑方法后,有必要思考这项技术的伦理、政治和法律影响。这项工作旨在对这些问题进行初步探讨。我不会关注CRISPR-Cas9在健康或环境领域的潜力,也不会关注它所涉及的所有伦理、法律和政治挑战。我主要关注使用CRISPR-Cas9改变人类种系的可能性。政府间组织就此主题发布了一些裁决。科学界也有一些关于此事的声明。了解他们提议暂停使用CRISPR-Cas9进行人类种系编辑的原因很重要。我在论文开头简要解释了CRISPR-Cas9的工作原理。