Johansson Ewa-Lena, Ternesten-Hasséus Ewa
Department of Physiotherapy and Occupational Therapy, Sahlgrenska University Hospital/Sahlgrenska, Gothenburg, Sweden.
Department of Respiratory Medicine and Allergology, Institution of Medicine, The Sahlgrenska Academy, University of Gothenburg, 413 45, Gothenburg, Sweden.
Lung. 2016 Dec;194(6):997-1005. doi: 10.1007/s00408-016-9937-5. Epub 2016 Sep 16.
Cough is a common symptom for which patients seek medical care and is defined as chronic if it has lasted for more than 8 weeks. The Hull Airway Reflux Questionnaire (HARQ) was developed with the aim of eliciting the major component of chronic cough. It comprises 14 items with a maximum total score of 70. A Swedish version (HARQ-S) has previously been developed but not yet formally validated. The aim of the present study was to validate the HARQ-S in terms of instrumental reliability and concurrent validity.
A total of 67 consecutively selected non-smoking patients with chronic cough and 91 non-smoking allegedly healthy controls were asked to answer two questionnaires, the HARQ-S and a local questionnaire, at two occasions about 3 weeks apart.
The HARQ-S showed good psychometric properties. The patients had significantly higher total scores (p < 0.001) compared to the controls, and the questionnaire showed outstanding discrimination ability to distinguish between patients and controls, with an area under the receiver operating characteristic curve of 0.99. Fifty patients and 77 controls completed the HARQ-S twice, showing good test-retest agreement in all items as well as in the total scores in both groups, and without any significant differences over time.
The Swedish version of the HARQ is a valid and reliable questionnaire with good agreement between the two measurements in both patients and controls. The HARQ-S has good reliability and validity and can be used as a diagnostic tool in Swedish-speaking patients with chronic cough.
咳嗽是患者寻求医疗护理的常见症状，若持续超过8周则被定义为慢性咳嗽。赫尔气道反流问卷（HARQ）旨在找出慢性咳嗽的主要构成因素。它包含14个项目，总分最高为70分。先前已开发出瑞典语版本（HARQ-S），但尚未进行正式验证。本研究的目的是在工具可靠性和同时效度方面验证HARQ-S。
连续选取67例非吸烟慢性咳嗽患者和91例据称健康的非吸烟对照者，要求他们在大约相隔3周的两个时间点回答两份问卷，即HARQ-S和一份本地问卷。
HARQ-S显示出良好的心理测量特性。与对照组相比，患者的总分显著更高（p < 0.001），并且该问卷在区分患者和对照组方面具有出色的辨别能力，受试者工作特征曲线下面积为0.99。50例患者和77例对照者完成了两次HARQ-S，两组在所有项目以及总分上均显示出良好的重测一致性，且随时间无任何显著差异。
HARQ的瑞典语版本是一份有效且可靠的问卷，在患者和对照组的两次测量之间具有良好的一致性。HARQ-S具有良好的可靠性和效度，可作为瑞典语慢性咳嗽患者的诊断工具。
