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光疗法历史简述

A brief report on the history of phototherapy.

作者信息

Grzybowski Andrzej, Sak Jarosław, Pawlikowski Jakub

机构信息

Department of Ophthalmology, Poznań City Hospital, ul. Szwajcarska 3, 61-285 Poznań, Poland; Chair of Ophthalmology, University of Warmia and Mazury, Warszawaska 30, 10-082 Olsztyn, Poland.

Department of Ethics and Human Philosophy, Medical University of Lublin, 20-059 Lublin, Staszica 4/6,102 (Collegium Maximum), Poland.

出版信息

Clin Dermatol. 2016 Sep-Oct;34(5):532-7. doi: 10.1016/j.clindermatol.2016.05.002. Epub 2016 May 20.

DOI:10.1016/j.clindermatol.2016.05.002
PMID:27638430
Abstract

From ancient times, light has played a significant role in the treatment of diseases. The modern discoveries (eg, ultraviolet radiation) and modern inventions (eg, the electric generator or the electric lightbulb), as well as balneologic experiences of the treatment with sunlight, contributed to the transition from heliotherapy to artificial light phototherapy at the end of the 19th century. Nils Ryberg Finsen (1860-1904) was the founder of modern phototherapy. He is famous for applying an electric carbon arc torch in treating patients with lupus vulgaris using ultraviolet radiation. Subsequently, phototherapy using artificial light sources gained importance in the treatment of skin diseases with a noninfectious etiology. William Henry Goeckerman (1884-1954) chose an ultraviolet B light to treat psoriasis. Improvement in the effectiveness of dermatologic phototherapy occurred in 1947, when methoxypsoralen was isolated. During the 20th century, phototherapy was applied to new therapeutic areas, such as neonatology, psychiatry, and ophthalmology.

摘要

从古代起,光就在疾病治疗中发挥了重要作用。现代的发现(如紫外线辐射)和现代的发明(如发电机或电灯泡),以及利用阳光进行治疗的浴疗经验,促使在19世纪末从日光疗法过渡到人工光光疗。尼尔斯·里伯格·芬森(1860 - 1904)是现代光疗的创始人。他因使用紫外线辐射的电弧灯治疗寻常狼疮患者而闻名。随后,使用人工光源的光疗在治疗非感染性病因的皮肤病方面变得重要起来。威廉·亨利·戈克曼(1884 - 1954)选择用紫外线B光治疗银屑病。1947年甲氧补骨脂素被分离出来后,皮肤科光疗的疗效得到了提高。在20世纪,光疗被应用于新的治疗领域,如新生儿科、精神病学和眼科。

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