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用于基于光的诊断和治疗的生物电子设备。

Bioelectronic devices for light-based diagnostics and therapies.

作者信息

Kim Han-Joon, Sritandi Weni, Xiong Ze, Ho John S

机构信息

Department of Electrical and Computer Engineering, National University of Singapore, Singapore.

出版信息

Biophys Rev (Melville). 2023 Jan 20;4(1):011304. doi: 10.1063/5.0102811. eCollection 2023 Mar.

Abstract

Light has broad applications in medicine as a tool for diagnosis and therapy. Recent advances in optical technology and bioelectronics have opened opportunities for wearable, ingestible, and implantable devices that use light to continuously monitor health and precisely treat diseases. In this review, we discuss recent progress in the development and application of light-based bioelectronic devices. We summarize the key features of the technologies underlying these devices, including light sources, light detectors, energy storage and harvesting, and wireless power and communications. We investigate the current state of bioelectronic devices for the continuous measurement of health and on-demand delivery of therapy. Finally, we highlight major challenges and opportunities associated with light-based bioelectronic devices and discuss their promise for enabling digital forms of health care.

摘要

光作为一种诊断和治疗工具在医学领域有着广泛的应用。光学技术和生物电子学的最新进展为可穿戴、可摄入和可植入设备带来了机遇,这些设备利用光来持续监测健康状况并精确治疗疾病。在本综述中,我们讨论了基于光的生物电子设备在开发和应用方面的最新进展。我们总结了这些设备所基于技术的关键特性,包括光源、光探测器、能量存储与收集以及无线供电和通信。我们研究了用于持续健康测量和按需治疗的生物电子设备的当前状态。最后,我们强调了与基于光的生物电子设备相关的主要挑战和机遇,并讨论了它们在实现数字形式医疗保健方面的前景。

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