Berrino F, Chiesa F, Carrassi A, Costa L, Pedroni C, Sala L, Spriano S, Squadrelli-Saraceno M, Tradati N, Toma S
Acta Otorhinolaryngol Ital. 1989;9 Suppl 23:1-24.
The NRC (National Research Council) task force on head and neck cancer issued this document to help clinicians involved in diagnosing and treating precancerous oral diseases. Chapter 1 includes definition, epidemiology, risk factors (alcohol, smoking, poor oral hygiene), WHO classification, clinical picture of leukoplakias, erythroplasia, lichen planus, as well as their natural history. Chapter 2 points out the clinical signs to be looked for in order to make a proper diagnosis and discusses biopsy techniques. Chapter 3 deals with therapeutic procedures (surgical technique and medical treatment), while Chapter 4 concerns follow-up according to the clinical and histological diagnosis. Finally, some statistical forms are enclosed: Form 1 consists of information regarding educational qualifications, occupation, alcohol consumption, smoking and dietary habits; Form 2 consists of information about previous diseases and the history of the present disease; Form 3 records the signs and symptoms observed for the precancerous lesion; Form 4 records treatment modalities; Form 5 records patient follow-up.
美国国家研究委员会（NRC）头颈癌特别工作组发布了这份文件，以帮助参与诊断和治疗口腔癌前疾病的临床医生。第1章包括定义、流行病学、危险因素（酒精、吸烟、口腔卫生不良）、世界卫生组织分类、白斑、红斑、扁平苔藓的临床表现及其自然史。第2章指出了为做出正确诊断而应寻找的临床体征，并讨论了活检技术。第3章涉及治疗程序（手术技术和药物治疗），而第4章涉及根据临床和组织学诊断进行的随访。最后，附上了一些统计表格：表格1包含有关学历、职业、饮酒、吸烟和饮食习惯的信息；表格2包含有关既往疾病和当前疾病病史的信息；表格3记录癌前病变观察到的体征和症状；表格4记录治疗方式；表格5记录患者随访情况。
