Fan Cancan, Wang Wenhui, Xu Tao, Zheng Shuguo
Department of Preventive Dentistry, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing, 100081, People's Republic of China.
BMC Oral Health. 2016 Sep 17;16(1):98. doi: 10.1186/s12903-016-0289-6.
The prevalence of early childhood caries (ECC) among children in Beijing, China, has been increasing continuously though slowly. However, there is limited information about ECC in Beijing. The aim of this study was to identify risk factors of dental caries among preschool children in Beijing.
For this case-control study, using a convenience sampling method, 787 children aged 3 and 4 years old were recruited; 386 children with caries constituted the early childhood caries (ECC) group and 401children without caries formed the caries-free (CF) group. Dental caries was diagnosed at the tooth surface level by two calibrated examiners according to the WHO 1997 criteria. A structured questionnaire was filled in by the children's main guardians. Mutans streptococci in non stimulated saliva and plaque were measured with the Dentocult SM Strip. Negative binomial regression was used for multivariate analysis.
Analysis of the data showed that level of mutans streptococci in dental plaque and history of dental visit were significantly correlated with the prevalence of caries and the mean dmfs score.
High level of plaque mutans streptococci is a risk factor for ECC in preschool children in Beijing. And longitudinal studies are needed to identify the causal relationships between the levels of mutans streptococci in dental plaque and caries development.
中国北京儿童早期龋(ECC)的患病率虽增长缓慢但呈持续上升趋势。然而,关于北京ECC的信息有限。本研究旨在确定北京学龄前儿童龋齿的危险因素。
在这项病例对照研究中,采用便利抽样法,招募了787名3至4岁的儿童;386名患龋儿童组成儿童早期龋(ECC)组,401名无龋儿童组成无龋(CF)组。由两名经过校准的检查人员根据世界卫生组织1997年标准在牙面水平诊断龋齿。儿童的主要监护人填写一份结构化问卷。使用Dentocult SM试纸条测量非刺激性唾液和牙菌斑中的变形链球菌。采用负二项回归进行多变量分析。
数据分析表明,牙菌斑中变形链球菌水平和就诊史与龋齿患病率及平均dmfs评分显著相关。
牙菌斑中高水平的变形链球菌是北京学龄前儿童患ECC的一个危险因素。需要进行纵向研究以确定牙菌斑中变形链球菌水平与龋齿发展之间的因果关系。