College of Pharmacy and Natural Medicine Research Institute, Mokpo National University, Muan-gun 58554, South Korea.
Department of Oriental Medicine Resource, Mokpo National University, Muan-gun 534-729, South Korea.
J Integr Med. 2016 Sep;14(5):359-73. doi: 10.1016/S2095-4964(16)60274-1.
Juglans regia Linn. (Juglandaceae), popularly known as English or Persian walnut, is a valuable medicinal plant with a potency to cure various diseases in traditional medicine. Since ancient time, different local ethnic groups have used various part of J. regia for a wide array of ailments including helminthiasis, diarrhea, sinusitis, stomach ache, arthritis, asthma, eczema, scrofula, skin disorders, diabetes mellitus, anorexia, thyroid dysfunction, cancer and infectious diseases. Biological activities of J. regia have been reported in several peer review journals and scientific attention is increasing. The present review attempts to provide comprehensive information on plant description, ethnobotanical use, toxicity, phytochemical profile, pharmacology, clinical studies and current research prospective of the J. regia. Currently, there is an immense interest on isolation/identification of active constituents from walnut and screening those active compounds for pharmacological activities. In addition, researchers are performing clinical trials as well as screening various solvent extracts or fractions of J. regia in several animal diseases models to identify promising therapeutic benefits. In the present work, we review the latest information based on published scientific investigations of J. regia.
欧洲山核桃（胡桃科），俗称英国或波斯核桃，是一种有价值的药用植物，在传统医学中具有治疗各种疾病的功效。自古以来，不同的地方族群就用欧洲山核桃的不同部位来治疗多种疾病，包括寄生虫病、腹泻、鼻窦炎、胃痛、关节炎、哮喘、湿疹、瘰疬、皮肤病、糖尿病、食欲不振、甲状腺功能障碍、癌症和传染病。在一些同行评议的期刊上已经报道了欧洲山核桃的生物活性，人们对它的关注度正在增加。本综述试图提供关于欧洲山核桃的植物描述、民族植物学用途、毒性、植物化学特征、药理学、临床研究和当前研究前景的综合信息。目前，人们对从核桃中分离/鉴定活性成分以及筛选这些活性化合物的药理活性非常感兴趣。此外，研究人员还在进行临床试验，并在几种动物疾病模型中筛选欧洲山核桃的各种溶剂提取物或馏分，以确定有希望的治疗益处。在本工作中，我们根据已发表的关于欧洲山核桃的科学研究综述了最新信息。
