对尼日利亚五家三级医疗机构中61例牙源性腺样瘤病例的回顾性研究。
A retrospective review of 61 cases of adenomatoid odontogenic tumour seen in five tertiary health facilities in Nigeria.
作者信息
Adisa Akinyele Olumuyiwa, Lawal Ahmed Oluwatoyin, Effiom Olajumoke Ajibola, Soyele Olujide Oladele, Omitola Olufemi Gbenga, Olawuyi Adetokunbo, Fomete Benjamin
机构信息
Department of Oral Pathology, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Department of Oral and Maxillofacial Pathology & Biology, College of Medicine, University of Lagos, Lagos, Nigeria.
出版信息
Pan Afr Med J. 2016 May 31;24:102. doi: 10.11604/pamj.2016.24.102.9400. eCollection 2016.
INTRODUCTION
Adenomatoid odontogenic tumor (AOT) is a benign lesion originating from the dental lamina or its remnants. It is a relatively uncommon neoplasm representing about 3% of all odontogenic tumors. The aim of this study was to examine the clinical and radiological characteristics of AOTs in five major tertiary centres in Nigeria.
METHODS
Archival hospital-based data stores of five tertiary health facilities in Nigeria were accessed. Case files and biopsy records were retrieved to obtain relevant information. Data was collected according to a proforma for standardization and entered into and analysed using SPSS for Windows (version 20.0; SPSS Inc. Chicago, IL).
RESULTS
61 (4.5%) cases of AOT were documented. The age range was 8-46 years with a mean age of 20.4±9.9 years. Male: Female ratio was 1:1.3. The anterior maxilla had 34 (55.8%) cases and the anterior mandible had 20 (32.8%) cases. 40 (65.6%) follicular cases, 20 (32.8%) extra-follicular cases and 1(1.6%) extra-osseous case were found. 31 cases (61.1%) were associated with impacted teeth and the upper canine was involved in 19 (57.6%) cases.
CONCLUSION
This study showed AOT to be more common in the maxilla, more in females, most often associated with impacted canines, however, the suggestion of AOT being a "Two third tumour" was not observed in this study.
引言
腺样牙源性肿瘤（AOT）是一种起源于牙板或其残余物的良性病变。它是一种相对罕见的肿瘤，约占所有牙源性肿瘤的3%。本研究的目的是检查尼日利亚五个主要三级医疗中心的腺样牙源性肿瘤的临床和放射学特征。
方法
访问了尼日利亚五个三级医疗机构基于医院档案的数据存储库。检索病例档案和活检记录以获取相关信息。根据标准化表格收集数据，并使用Windows版SPSS（版本20.0；SPSS公司，伊利诺伊州芝加哥）输入并进行分析。
结果
记录了61例（4.5%）腺样牙源性肿瘤病例。年龄范围为8至46岁，平均年龄为20.4±9.9岁。男女比例为1:1.3。上颌前部有34例（55.8%），下颌前部有20例（32.8%）。发现40例（65.6%）滤泡型病例、20例（32.8%）非滤泡型病例和1例（1.6%）骨外型病例。31例（61.1%）与阻生牙有关，其中上颌尖牙受累19例（57.6%）。
结论
本研究表明腺样牙源性肿瘤在上颌更常见，女性更多见，最常与阻生尖牙有关，然而，本研究未观察到腺样牙源性肿瘤是“三分之二肿瘤”的迹象。
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