在手术室中使用二硫苏糖醇清除主动脉瓣生物膜上的细菌：1例由金黄色葡萄球菌和奇异变形杆菌引起的感染性心内膜炎病例
Use of Dithiothreitol to Dislodge Bacteria From the Biofilm on an Aortic Valve in the Operating Theatre: A Case of Infective Endocarditis Caused by Staphylococcus aureus and Proteus mirabilis.
作者信息
Rimoldi Sara G, De Vecchi Elena, Pagani Cristina, Zambelli Agostino, Di Gregorio Annamaria, Bosisio Enrica, Vanelli Paolo, Scrofani Roberto, Gismondo Maria R, Cagnoni Giovanni, Antona Carlo
机构信息
Laboratorio di Microbiologia Clinica, Virologia e Diagnostica delle Bioemergenze, ASST Fatebenefratelli Sacco-Polo Universitario, Milan, Italy.
Laboratorio di Analisi Chimico-Cliniche e Microbiologiche-IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
出版信息
Ann Thorac Surg. 2016 Oct;102(4):e357-9. doi: 10.1016/j.athoracsur.2016.03.023.
This is the first reported case of 2 biofilm-producing bacteria, Staphylococcus aureus and Proteus mirabilis, identified from an aortic valve using an innovative device with dithiothreitol solution, able to dislodge bacterial biofilm. The method is usable in the operating theatre and recommended in infective endocarditis nonresponders to empiric therapy.
这是首例报告的使用含二硫苏糖醇溶液的创新装置从主动脉瓣中鉴定出两种产生物膜细菌——金黄色葡萄球菌和奇异变形杆菌的病例，该装置能够去除细菌生物膜。该方法可在手术室使用，推荐用于对经验性治疗无反应的感染性心内膜炎患者。
Zotero 插件