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潜伏性结核相关性巩膜炎:一例报告

Latent tuberculosis-related scleritis: a case report.

作者信息

Lhaj Houssaine Ait, Benjelloun Amine, Bouia Youssef, Bennouk Youssef, Mouzari Yassine, Kamouni Youssef El, Kriet Mohamed

机构信息

Ophtalmology Unit, Avicenne Military Hospital, Marrakech, Morocco.

Pulmonology Unit, Avicenne Military Hospital, Marrakech, Morocco.

出版信息

BMC Res Notes. 2016 Sep 20;9(1):446. doi: 10.1186/s13104-016-2251-8.

DOI:10.1186/s13104-016-2251-8
PMID:27646473
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5029063/
Abstract

BACKGROUND

Scleritis is a painful inflammatory process centered in the sclera that may involve the cornea and the underlying uvea. The etiology is commonly idiopathic or autoimmune but some cases are associated with systemic infection such as tuberculosis.

CASE PRESENTATION

In this report, we describe an unusual case of a female Moroccan patient who had a long history of bilateral recurrent scleritis associated with peripheral keratopathy and anterior uveitis. The patient was diagnosed with latent tuberculosis and responded to antitubercular therapy administrated after exclusion of other aetiologies. This patient was finally diagnosed with latent tuberculosis- related scleritis.

CONCLUSIONS

Although systemic tuberculosis is reported as a possible cause of scleritis and other ocular inflammatory manifestations, assessment of the diagnosis of tuberculosis-related ocular inflammation is challenging especially in latent forms. The treatment is largely presumptive. However, a favorable response to antitubercular therapy without relapse is taken as evidence of the disease.

摘要

背景

巩膜炎是一种以巩膜为中心的疼痛性炎症过程,可累及角膜及下方的葡萄膜。病因通常为特发性或自身免疫性,但部分病例与系统性感染如结核病相关。

病例报告

在本报告中,我们描述了一例不寻常的摩洛哥女性患者,她有双侧复发性巩膜炎伴周边角膜病变和前葡萄膜炎的长期病史。该患者被诊断为潜伏性结核病,在排除其他病因后接受抗结核治疗,病情好转。该患者最终被诊断为潜伏性结核相关性巩膜炎。

结论

尽管系统性结核病被报道为巩膜炎及其他眼部炎症表现的可能病因,但结核相关性眼部炎症的诊断评估具有挑战性,尤其是在潜伏形式中。治疗很大程度上是推测性的。然而,对抗结核治疗有良好反应且无复发被视为该病的证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6e0/5029063/191fd9e6be00/13104_2016_2251_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6e0/5029063/7fbf29010ff0/13104_2016_2251_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6e0/5029063/191fd9e6be00/13104_2016_2251_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6e0/5029063/7fbf29010ff0/13104_2016_2251_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6e0/5029063/191fd9e6be00/13104_2016_2251_Fig2_HTML.jpg

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