Ozkul Faruk, Erbis Halil, Yilmaz Vural Taner, Kocak Huseyin, Osmanoglu Ibrahim Ali, Dinckan Ayhan
Faruk Ozkul, Department of General Surgery, School of Medicine, Canakkale Onsekiz Mart University, Canakkale, Turkey.
Halil Erbis, Department of General Surgery, School of Medicine, Akdeniz University, Antalya, Turkey.
Pak J Med Sci. 2016 Jul-Aug;32(4):827-30. doi: 10.12669/pjms.324.10094.
To analyze the effects of old age on renal transplantation (Tx) results and graft survival, and compared elderly patient population with the young patients.
A total of 1946 renal transplant were performed from 1537 living and 409 cadaveric donors between 2003 and 2014. The recipients were divided into two groups according to their age at the time of transplantation. The young age group consisted of 18-59-year-old, and the elderly group consisted of the ones ≥ 60 years.
Acute rejection was seen in 19.5% of the young age group while this rate was 16.7% in the old age group (p=0.535). DGF was seen in 6.3% of the young age group, and in 13.5% of the old age group (p<0.001). Analysis of the overall survival rates demonstrated that 1.6% of the patients in the young age group and 6.8% of the patients in the old age groups died (p=0.003).
Renal transplant had high graft survival rates in the elderly as in the young patients. However, the risks for complications were higher in the older age group compared to the younger age group. Thus, it is important to make a careful selection among elderly candidates for renal transplantation.
分析高龄对肾移植结果及移植物存活的影响，并将老年患者群体与年轻患者进行比较。
2003年至2014年间，共进行了1946例肾移植手术，供体包括1537例活体供体和409例尸体供体。根据移植时的年龄将受者分为两组。年轻组为18至59岁，老年组为60岁及以上。
年轻组急性排斥反应发生率为19.5%，老年组为16.7%（p = 0.535）。年轻组移植肾功能延迟恢复（DGF）发生率为6.3%，老年组为13.5%（p < 0.001）。总体生存率分析表明，年轻组患者死亡率为1.6%，老年组为6.8%（p = 0.003）。
肾移植在老年患者中的移植物存活率与年轻患者一样高。然而，老年组并发症风险高于年轻组。因此，在老年肾移植候选者中进行仔细筛选很重要。
