前颅底脑脊液漏的管理
Management of Anterior Skull Base Cerebrospinal Fluid Leaks.
作者信息
Le Christopher, Strong E Bradley, Luu Quang
机构信息
Department of Otolaryngology, University of California, Davis, Sacramento, California, United States.
出版信息
J Neurol Surg B Skull Base. 2016 Oct;77(5):404-11. doi: 10.1055/s-0036-1584229. Epub 2016 Jun 2.
Abstract
Cerebrospinal fluid (CSF) leak occurs from traumatic, iatrogenic, and idiopathic etiologies. Its timely diagnosis requires clinical, radiographic, and laboratory testing. Medical and surgical management can mitigate the risk of life-threatening infection and morbidity. This article outlines the pathophysiology, diagnosis, and management or CSF leak of the anterior skull base.
摘要
脑脊液（CSF）漏可由创伤性、医源性和特发性病因引起。其及时诊断需要临床、影像学和实验室检查。药物和手术治疗可降低危及生命的感染和发病风险。本文概述了前颅底脑脊液漏的病理生理学、诊断及治疗。
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本文引用的文献
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Diagnosis and treatment of cerebrospinal fluid rhinorrhea following accidental traumatic anterior skull base fractures.外伤性前颅底骨折后脑脊液鼻漏的诊断和治疗。
Neurosurg Focus. 2012 Jun;32(6):E3. doi: 10.3171/2012.4.FOCUS1244.
2
A management algorithm for cerebrospinal fluid leak associated with anterior skull base fractures: detailed clinical and radiological follow-up.一种与前颅底骨折相关的脑脊液漏的管理算法：详细的临床和影像学随访。
Neurosurg Rev. 2012 Apr;35(2):227-37; discussion 237-8. doi: 10.1007/s10143-011-0352-3. Epub 2011 Sep 27.
3
Antibiotic prophylaxis for preventing meningitis in patients with basilar skull fractures.用于预防颅底骨折患者脑膜炎的抗生素预防性治疗。
Cochrane Database Syst Rev. 2011 Aug 10(8):CD004884. doi: 10.1002/14651858.CD004884.pub3.
4
Traumatic cerebrospinal fluid leaks.创伤性脑脊液漏
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5
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6
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8
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9
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10
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Acta Neurochir (Wien). 2008 Sep;150(9):897-900; discussion 900. doi: 10.1007/s00701-008-0005-7. Epub 2008 Aug 23.
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