Translational Advances in the Field of Pulmonary Hypertension. Translating MicroRNA Biology in Pulmonary Hypertension. It Will Take More Than "miR" Words.
作者信息
Chun Hyung J, Bonnet Sébastien, Chan Stephen Y
机构信息
1 Section of Cardiovascular Medicine, Department of Internal Medicine, Yale Cardiovascular Research Center, Yale University School of Medicine, New Haven, Connecticut.
2 Pulmonary Hypertension Research Group, Quebec Heart and Lung Institute Research Centre, University of Laval, Quebec City, Quebec, Canada; and.
出版信息
Am J Respir Crit Care Med. 2017 Jan 15;195(2):167-178. doi: 10.1164/rccm.201604-0886PP.
Abstract
摘要
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Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension.血管僵硬通过机械激活YAP/TAZ依赖的谷氨酰胺分解来驱动肺动脉高压。
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DNA Damage and Pulmonary Hypertension.DNA损伤与肺动脉高压
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