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酷似间变性甲状腺癌的Riedel甲状腺炎:不寻常的表现。

Riedel's Thyroiditis Mimicking as Anaplastic Thyroid Carcinoma: Unusual Presentation.

作者信息

Hakeem Arsheed Hussain, Chandramathyamma Sreerenjini Kaithaparambil, Hakeem Imtiyaz Hussain, Wani Fozia Jeelani, Gomez Ramesh

机构信息

Department of Head and Neck Oncology, Apollo Cancer Hospitals, Hyderabad, 500096 India.

Department of Histopathology, Lakeshore Hospital and Research Center, Maradu Kochi, Kerala India.

出版信息

Indian J Surg Oncol. 2016 Sep;7(3):359-62. doi: 10.1007/s13193-016-0513-5. Epub 2016 Feb 24.

DOI:10.1007/s13193-016-0513-5
PMID:27651702
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5016331/
Abstract

Riedel's thyroiditis is a rare inflammatory process which not only involves thyroid gland but also the surrounding vital structures. It may also be associated with various forms of systemic fibrotic disorders. The exact etiology is not known, but currently most favored view is that of a localized form of systemic fibrotic process. We report a case of Riedel's thyroiditis in a patient, highlighting a rare presentation mimicking anaplastic carcinoma. Clinical awareness of such presentation of Riedel's thyroiditis would enhance our ability to make this diagnosis promptly. Apart from avoiding or minimizing aggressive surgical intervention, awareness of such clinical entity may avoid complications and hence morbidity. Our case also highlights the difficulty in histological diagnosis which is very important to rule out malignancy and avoiding any major surgical intervention fraught with complications. Good response to high dose steroids as seen in our case is the current accepted treatment of choice.

摘要

里德尔甲状腺炎是一种罕见的炎症过程,不仅累及甲状腺,还累及周围重要结构。它也可能与各种形式的系统性纤维化疾病相关。确切病因尚不清楚,但目前最受青睐的观点是局部形式的系统性纤维化过程。我们报告一例里德尔甲状腺炎患者,突出了一种罕见的表现,酷似间变性癌。对里德尔甲状腺炎这种表现的临床认识将提高我们及时做出诊断的能力。除了避免或尽量减少激进的手术干预外,对这种临床实体的认识可以避免并发症,从而降低发病率。我们的病例还突出了组织学诊断的困难,这对于排除恶性肿瘤和避免任何充满并发症的重大手术干预非常重要。如我们病例中所见,对高剂量类固醇的良好反应是目前公认的治疗选择。

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