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评估埃及前臂骨折儿童的骨骼健康:一项病例对照研究。

Evaluating Bone Health in Egyptian Children with Forearm Fractures: A Case Control Study.

作者信息

El-Sakka Abeer, Penon Cristina, Hegazy Adham, Elbatrawy Salwa, Gobashy Amr, Moreira Alvaro

机构信息

Department of Pediatrics, Ain Shams University Medical School, Cairo, Egypt.

Department of Pediatrics, University of Texas Health Science Center, San Antonio, TX, USA.

出版信息

Int J Pediatr. 2016;2016:7297092. doi: 10.1155/2016/7297092. Epub 2016 Aug 29.

Abstract

Objective. To determine the likelihood of vitamin D deficiency and low bone mineral density in Egyptian children with forearm fractures. Methods. A case control study of 46 children aged 3 to 10 years with or without forearm fractures. Validated questionnaires were used to assess calcium and vitamin D intake as well as sun exposure. Serum calcium, phosphorus, alkaline phosphatase, and 25-hydroxy-vitamin D were collected. Bone mineral density was evaluated using dual-energy X-ray absorptiometry. Results. Compared to the Control group, calcium and vitamin D intake was lower in the Cases group (p = 0.03). Cases had higher Body Mass Index than Controls, p = 0.01. Children in the Cases group had lower mean serum calcium values 8.3 ± 1.4 compared to 9.3 ± 1.1 in Controls (p = 0.01). Alkaline phosphatase was higher in Cases 265 ± 65.8 than Controls 226 ± 54.6 (p = 0.03). Vitamin D and bone mineral density scores were significantly lower in the Cases group (p < 0.05). Conclusion. Our data shows an increased rate of vitamin D deficiency and decreased bone mineral density in Egyptian children with forearm fractures.

摘要

目的。确定埃及前臂骨折儿童维生素D缺乏和低骨矿物质密度的可能性。方法。对46名3至10岁有或无前臂骨折的儿童进行病例对照研究。使用经过验证的问卷评估钙和维生素D的摄入量以及阳光照射情况。收集血清钙、磷、碱性磷酸酶和25-羟基维生素D。使用双能X线吸收法评估骨矿物质密度。结果。与对照组相比,病例组的钙和维生素D摄入量较低(p = 0.03)。病例组的体重指数高于对照组,p = 0.01。病例组儿童的平均血清钙值较低,为8.3±1.4,而对照组为9.3±1.1(p = 0.01)。病例组的碱性磷酸酶较高,为265±65.8,而对照组为226±54.6(p = 0.03)。病例组的维生素D和骨矿物质密度评分显著较低(p < 0.05)。结论。我们的数据显示,埃及前臂骨折儿童维生素D缺乏率增加,骨矿物质密度降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2173/5019920/d8e1ca276a13/IJPEDI2016-7297092.001.jpg

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