Lamm G
ERICA Data Centre, Institute for Clinical Social Medicine, University Medical Clinic, Heidelberg, F.R.G.
Ann Med. 1989 Jun;21(3):189-92. doi: 10.3109/07853898909149931.
In Europe around 1970 there were only a few small and often poorly known epidemiological studies on risk factors and the incidence of coronary heart disease. In order to enhance the utilization of the information contained in them, the Medical Clinic in Heidelberg offered uniform data analysis to qualifying contributing centres. Thirty-five studies from 17 countries joined this WHO project covering a total sample of 151,923 men and women. The first objective was to draw up a risk distribution map of Europe that would help to understand changes in cardiovascular disease mortality. In this first report the geographical distribution of the four main risk factors--blood pressure, cholesterol, smoking, and weight--is presented together with an overall risk estimate. The well known north-west--east-south decrement in coronary heart disease mortality is clearly supported by this analysis. The second publication will deal with multivariate risk prediction calculated from European data.
1970年左右在欧洲,关于冠心病风险因素和发病率的小型流行病学研究为数不多,而且常常鲜为人知。为了提高对其中所含信息的利用率,海德堡的内科诊所为符合条件的参与中心提供统一的数据分析。来自17个国家的35项研究加入了这个世界卫生组织项目,样本总数为151,923名男性和女性。首要目标是绘制一幅欧洲风险分布图,以帮助了解心血管疾病死亡率的变化。在这份首份报告中,呈现了血压、胆固醇、吸烟和体重这四个主要风险因素的地理分布以及总体风险评估。这一分析明确支持了冠心病死亡率从西北向东南递减这一广为人知的现象。第二篇出版物将论述根据欧洲数据计算得出的多变量风险预测。