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中国城市成年人群中高血压前期及未诊断高血压的情况:一项基于人群的横断面研究。

Pre- and undiagnosed-hypertension in urban Chinese adults: a population-based cross-sectional study.

作者信息

Zhang H, Deng M, Xu H, Wang H, Song F, Bao C, Paillard-Borg S, Xu W, Qi X

机构信息

Department of Epidemiology and Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China.

Department of Fundamental Nursing, School of Nursing, Tianjin Medical University, Tianjin, China.

出版信息

J Hum Hypertens. 2017 Apr;31(4):263-269. doi: 10.1038/jhh.2016.73. Epub 2016 Sep 22.

Abstract

Hypertension is common in adults and often undiagnosed, and the prevalence of pre- and undiagnosed-hypertension remains unclear. We aimed to investigate the prevalence of pre- and undiagnosed-hypertension and their correlates among urban Chinese adults. A total of 7435 participants aged 20-79 were included in this study. Data on demographics, lifestyle and medical history were collected through a structured interview. Pre- and undiagnosed-hypertension was defined as systolic blood pressure/ diastolic blood pressure (SBP/DBP) of 120-139/80-89 mm Hg and SBP⩾140 mm Hg and/or DBP⩾90 mm Hg, respectively, in participants without a history of hypertension and use of antihypertensive medication. Prevalence rates were calculated and standardized using local age- and gender-specific census data. Data were analysed using multinomial logistic regression with adjustment for potential confounders. Of all the participants, 2726 (36.7%) were diagnosed with pre-hypertension and 919 (12.3%) with undiagnosed-hypertension. Undiagnosed-hypertension accounted for 37.3% of all participants with hypertension. The prevalence of pre-hypertension gradually decreased with age, while undiagnosed-hypertension increased, although presenting different changing patterns among men and women. In a fully adjusted multinomial logistic regression, age, male sex, low socio-economic status (SES), abdominal obesity, alcohol drinking, physical inactivity and type 2 diabetes mellitus (T2DM) were significantly associated with increased odds of pre- and undiagnosed-hypertension. In conclusions, the prevalence of pre- and undiagnosed-hypertension was ~50% among urban Chinese adults. Abdominal obesity, low SES, alcohol drinking, physical inactivity and T2DM may be indicators for pre- and undiagnosed-hypertension.

摘要

高血压在成年人中很常见,且常常未被诊断出来,而前期高血压和未诊断高血压的患病率仍不明确。我们旨在调查中国城市成年人群中前期高血压和未诊断高血压的患病率及其相关因素。本研究共纳入了7435名年龄在20 - 79岁的参与者。通过结构化访谈收集了人口统计学、生活方式和病史等数据。前期高血压和未诊断高血压分别定义为:在无高血压病史且未使用抗高血压药物的参与者中,收缩压/舒张压(SBP/DBP)为120 - 139/80 - 89 mmHg以及SBP≥140 mmHg和/或DBP≥90 mmHg。患病率采用当地年龄和性别特异性人口普查数据进行计算和标准化。使用多项逻辑回归分析数据,并对潜在混杂因素进行调整。在所有参与者中,2726人(36.7%)被诊断为前期高血压,919人(12.3%)被诊断为未诊断高血压。未诊断高血压占所有高血压参与者的37.3%。前期高血压的患病率随年龄增长逐渐下降,而未诊断高血压的患病率则上升,尽管男性和女性呈现出不同的变化模式。在完全调整的多项逻辑回归分析中,年龄、男性、低社会经济地位(SES)、腹型肥胖、饮酒、缺乏身体活动和2型糖尿病(T2DM)与前期高血压和未诊断高血压的患病几率增加显著相关。总之,中国城市成年人群中前期高血压和未诊断高血压的患病率约为50%。腹型肥胖、低SES、饮酒、缺乏身体活动和T2DM可能是前期高血压和未诊断高血压的指标。

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