Augustin J, Schäfer I, Reusch M, Augustin M
CVderm - Competenzzentrum Versorgungsforschung in der Dermatologie, Institut für Versorgungsforschung in der Dermatologie und bei Pflegeberufen, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Deutschland.
Dermatologische Gemeinschaftspraxis am Tibarg, Institut für Strategische Analysen in der Dermatologie (IStAD), Hamburg, Deutschland.
Hautarzt. 2016 Dec;67(12):996-1002. doi: 10.1007/s00105-016-3876-1.
Mortality and lethality of malignant melanoma (MM) show marked variations throughout Europe, thereunder a higher risk within the Netherlands (NL) when compared to Germany (D).
Comparison of systems and exploration of possible causal factors that could explain the difference between D and NL. Comparative healthcare research analysis using published international literature, as well as publicly accessible databases, and a subsequent hypothesis-generating analysis.
The higher rate of excised MM less than 1 mm in diameter in D (65 % vs. 45 %) confirms the clinical reports of the cancer registries. The biological factors for the emergence of MM, such as skin type, do not seem to significantly differ from each other. Among the further potential predictors there are no relevant differences within, for example, geographical conditions and the qualifications of the treating physicians. Primary prevention has a longer continual tradition in D. Here, secondary prevention is characterized by population-based extensive screening, which does not occur within the NL. In addition, distinct differences are found regarding access to dermatologists.
System access to a medical specialist and the prevention of skin cancer are currently the most distinctive potential determinants of more favorable MM survival rate in Germany.
恶性黑色素瘤(MM)的死亡率和致死率在欧洲各地存在显著差异,其中荷兰(NL)的风险高于德国(D)。
比较相关系统并探究可能解释D和NL之间差异的因果因素。使用已发表的国际文献以及可公开获取的数据库进行比较卫生保健研究分析,随后进行假设生成分析。
D中直径小于1毫米的MM切除率较高(65%对45%),这证实了癌症登记处的临床报告。MM出现的生物学因素,如皮肤类型,似乎彼此之间没有显著差异。在其他潜在预测因素中,例如地理条件和治疗医生的资质方面没有相关差异。D的一级预防传统更为悠久。在这里,二级预防的特点是基于人群的广泛筛查,而NL则没有。此外,在皮肤科医生的可及性方面发现了明显差异。
目前,在德国,获得医学专家服务的途径和皮肤癌预防是MM生存率更有利的最显著潜在决定因素。