Pérez-Zepeda M U, Gutiérrez-Robledo L M
Geriatric Epidemiology Department at National Institute of Geriatrics, Mexico City, Mexico.
Head Office of the National Institute of Geriatrics, Periférico Sur 2767, colonia San Jerónimo Lídice, delegación Magdalena Contreras, 10200 México Distrito Federal, Mexico City, Mexico.
Eur Geriatr Med. 2016 Jun;7(3):262-266. doi: 10.1016/j.eurger.2016.01.004. Epub 2016 Feb 17.
Calf circumference is a surrogate measurement of muscle mass. However, there is scarce evidence on its validity in predicting adverse outcomes such as mobility disability. The aim of this report is to determine if calf circumference could predict incident mobility disability in Mexican 60-year or older adults.
This is a secondary analysis of the Mexican Health and Aging Study and in particular of its two first waves. Sixty-year or older adults without mobility disability in the first assessment were included and followed-up for two years. Calf circumference quartile groups were compared to test the difference of incident mobility disability. Logistic regression models were fitted to test the independent association when including confounding variables.
A total of 745 older adults were assessed, from which 24.4% of the older adults developed mobility disability at follow-up. A calf circumference > 38 cm was associated with a higher risk of developing mobility disability, even after adjustment in the multivariate model, with an odds ratio 0.55 (95% confidence interval 0.31-0.99, = 0.049).
High calf circumference in Mexican older adults is independently associated with incident mobility disability. This could reflect the impact of adverse health conditions such as obesity (with high fat tissue) or edema. Further research should aim at testing these results in different populations.
小腿围是肌肉量的替代测量指标。然而，关于其在预测诸如行动不便等不良结局方面的有效性的证据很少。本报告的目的是确定小腿围是否能够预测墨西哥60岁及以上成年人发生行动不便的情况。
这是对墨西哥健康与老龄化研究，特别是其前两波数据的二次分析。纳入首次评估时无行动不便的60岁及以上成年人，并随访两年。比较小腿围四分位数组以检验行动不便发生率的差异。纳入混杂变量时，采用逻辑回归模型检验独立关联。
共评估了745名老年人，其中24.4%的老年人在随访期间出现了行动不便。即使在多变量模型中进行调整后，小腿围>38 cm与发生行动不便的较高风险相关，比值比为0.55（95%置信区间0.31 - 0.99，P = 0.049）。
墨西哥老年人小腿围较高与发生行动不便独立相关。这可能反映了肥胖（高脂肪组织）或水肿等不良健康状况的影响。进一步的研究应旨在在不同人群中验证这些结果。
