Mirza Nazima, Ganguly Barna
Associate Professor, Department of Pharmacology, P.S. Medical College , Karamsad, Gujarat, India .
Professor and Head, Department of Pharmacology, P.S. Medical College , Karamsad, Gujarat, India .
J Clin Diagn Res. 2016 Aug;10(8):FC05-9. doi: 10.7860/JCDR/2016/20600.8298. Epub 2016 Aug 1.
In India, medicines are procured with prescription or without prescription by patients, which are kept at home and often are utilized in inappropriate manner. It may remain unused, get expired or may be repeated in the way of self medication. So there remains an increase chance of self-medication compared to prescribed drugs.
This study was aimed to explore the utilization pattern of medicines available at home with special attention to the types of medicine (with or without prescription) and their appropriate utilization (dosage compliance) and intended self-medication.
A cross-sectional study was conducted in Anand district of Gujarat, India during the year 2012- 2014 after Human Research Ethics Committee (HREC) approval. Data were collected from 800 houses, 400 each from urban and rural areas and then analysed for the details of medicines available in the house as: (i) number of homes having medicines; (ii) number of formulations with and without prescriptions; (iii) number of formulations with package inserts & expired formulations; (iv) Dosage forms of medicines; (v) pharmacological class wise distribution of medicines; (vi) status of the medicine use whether for current use, future use or leftover; and (vii) Appropriateness of medicines with and without prescription in relation to dose and duration of treatment.
Medicines were available in 93.75% houses. More medicine formulations (16.76%) were found without prescription in urban area than in rural (11.82%). Highest number of dosage forms found, were that of tablets (62%). Among the prescribed medicines, majority of medicines were from cardiovascular disease (19.88%) and from without prescription medicines, Non-Steroidal Antiinflammatory Drugs (NSAIDs) were the major group available at houses (35.13%). The leftover medicines with prescription were 20.39% and without prescription medicines were 13.37%. Appropriate dose and duration of medicines were followed more significantly by urban people than the rural. Only 2.91% medicines were found along with package inserts and 2.94% crossed the expiry dates.
The evaluation of utilization of medicines, in urban and rural population describes high drug storage, higher leftover medicines and inappropriate use of medicines and many self medicated by patients which suggests the need to educate the patients about proper and rational use of medicines.
在印度,患者可凭处方或无处方购买药品,这些药品存放在家中,且常常被不当使用。药品可能未被使用、过期或被用于自我药疗。因此,与处方药相比,自我药疗的可能性增加。
本研究旨在探讨家庭中现有药品的使用模式,特别关注药品类型(有处方或无处方)及其合理使用(剂量依从性)和自我药疗情况。
2012年至2014年期间,在印度古吉拉特邦阿南德地区进行了一项横断面研究,该研究经人类研究伦理委员会(HREC)批准。从800户家庭收集数据,城乡各400户,然后分析家庭中现有药品的详细情况,包括:(i)有药品的家庭数量;(ii)有处方和无处方的制剂数量;(iii)有包装说明书和过期制剂的数量;(iv)药品剂型;(v)药品按药理类别分布情况;(vi)药品使用状态,即当前使用、未来使用或剩余;以及(vii)有处方和无处方药品在剂量和治疗持续时间方面的合理性。
93.75%的家庭有药品。城市地区无处方的药品制剂(16.76%)比农村地区(11.82%)多。发现数量最多的剂型是片剂(62%)。在处方药中,大多数药品来自心血管疾病类(19.88%),在非处方药中,非甾体抗炎药(NSAIDs)是家庭中主要的药品类别(35.13%)。有处方的剩余药品为20.39%,无处方的剩余药品为13.37%。城市居民比农村居民更显著地遵循药品的适当剂量和疗程。仅2.91%的药品配有包装说明书,2.94%的药品过期。
对城乡居民药品使用情况的评估表明,药品储存量高、剩余药品多、药品使用不当,且许多患者进行自我药疗,这表明需要对患者进行合理用药教育。