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手机记录的心音信号的自动信号质量评估

Automated signal quality assessment of mobile phone-recorded heart sound signals.

作者信息

Springer David B, Brennan Thomas, Ntusi Ntobeko, Abdelrahman Hassan Y, Zühlke Liesl J, Mayosi Bongani M, Tarassenko Lionel, Clifford Gari D

机构信息

a Department of Engineering Science , University of Oxford , Oxford , UK.

b Department of Medicine , Groote Schuur Hospital , Cape Town , South Africa.

出版信息

J Med Eng Technol. 2016 Oct-Nov;40(7-8):342-355. doi: 10.1080/03091902.2016.1213902. Epub 2016 Sep 23.

Abstract

Mobile phones, due to their audio processing capabilities, have the potential to facilitate the diagnosis of heart disease through automated auscultation. However, such a platform is likely to be used by non-experts, and hence, it is essential that such a device is able to automatically differentiate poor quality from diagnostically useful recordings since non-experts are more likely to make poor-quality recordings. This paper investigates the automated signal quality assessment of heart sound recordings performed using both mobile phone-based and commercial medical-grade electronic stethoscopes. The recordings, each 60 s long, were taken from 151 random adult individuals with varying diagnoses referred to a cardiac clinic and were professionally annotated by five experts. A mean voting procedure was used to compute a final quality label for each recording. Nine signal quality indices were defined and calculated for each recording. A logistic regression model for classifying binary quality was then trained and tested. The inter-rater agreement level for the stethoscope and mobile phone recordings was measured using Conger's kappa for multiclass sets and found to be 0.24 and 0.54, respectively. One-third of all the mobile phone-recorded phonocardiogram (PCG) signals were found to be of sufficient quality for analysis. The classifier was able to distinguish good- and poor-quality mobile phone recordings with 82.2% accuracy, and those made with the electronic stethoscope with an accuracy of 86.5%. We conclude that our classification approach provides a mechanism for substantially improving auscultation recordings by non-experts. This work is the first systematic evaluation of a PCG signal quality classification algorithm (using a separate test dataset) and assessment of the quality of PCG recordings captured by non-experts, using both a medical-grade digital stethoscope and a mobile phone.

摘要

由于手机具备音频处理能力,因此有潜力通过自动听诊来辅助心脏病诊断。然而,这样的平台可能会被非专业人员使用,所以,由于非专业人员更有可能录制质量较差的音频,该设备必须能够自动区分质量差的录音和具有诊断价值的录音。本文研究了使用基于手机的设备和商用医疗级电子听诊器进行心音录音的自动信号质量评估。这些时长均为60秒的录音取自151名随机选取的、患有不同疾病的成年患者,这些患者均前往心脏科诊所就诊,且由五名专家进行了专业注释。采用平均投票程序为每个录音计算最终的质量标签。为每个录音定义并计算了九个信号质量指标。然后训练并测试了用于对二元质量进行分类的逻辑回归模型。使用适用于多类集的康格卡方检验来衡量听诊器和手机录音的评分者间一致性水平,结果发现分别为0.24和0.54。结果发现,所有手机录制的心音图(PCG)信号中有三分之一的质量足以进行分析。该分类器能够以82.2%的准确率区分手机录制的高质量和低质量录音,对于电子听诊器录制的录音,准确率为86.5%。我们得出结论,我们的分类方法提供了一种机制,可大幅改善非专业人员的听诊录音。这项工作是对PCG信号质量分类算法的首次系统评估(使用单独的测试数据集),也是对非专业人员使用医疗级数字听诊器和手机采集的PCG录音质量的评估。

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