School of Biomedical Engineering, Dalian University of Technology, Dalian 116024, China.
Liaoning Key Lab of Integrated Circuit and Biomedical Electronic System, China.
Biomed Res Int. 2021 Feb 24;2021:7565398. doi: 10.1155/2021/7565398. eCollection 2021.
Automated heart sound signal quality assessment is a necessary step for reliable analysis of heart sound signal. An unavoidable processing step for this objective is the heart sound segmentation, which is still a challenging task from a technical viewpoint. In this study, ten features are defined to evaluate the quality of heart sound signal without segmentation. The ten features come from kurtosis, energy ratio, frequency-smoothed envelope, and degree of sound periodicity, where five of them are novel in signal quality assessment. We have collected a total of 7893 recordings from open public heart sound databases and performed manual annotation for each recording as gold standard quality label. The signal quality is classified based on two schemes: binary classification ("unacceptable" and "acceptable") and triple classification ("unacceptable", "good," and "excellent"). Sequential forward feature selection shows that the feature "the degree of periodicity" gives an accuracy rate of 73.1% in binary SVM classification. The top five features dominate the classification performance and give an accuracy rate of 92%. The binary classifier has excellent generalization ability since the accuracy rate reaches to (90.4 ± 0.5) % even if 10% of the data is used to train the classifier. The rate increases to (94.3 ± 0.7) % in 10-fold validation. The triple classification has an accuracy rate of (85.7 ± 0.6) % in 10-fold validation. The results verify the effectiveness of the signal quality assessment, which could serve as a potential candidate as a preprocessing in future automatic heart sound analysis in clinical application.
自动心音信号质量评估是可靠分析心音信号的必要步骤。为了实现这一目标,不可避免的处理步骤是心音分段,从技术角度来看,这仍然是一项具有挑战性的任务。在这项研究中,定义了十个特征来评估无需分段的心音信号的质量。这十个特征来自峰度、能量比、频率平滑包络和声音周期性程度,其中五个特征在信号质量评估中是新颖的。我们从公开的心音数据库中总共收集了 7893 条记录,并对每条记录进行了人工注释作为黄金标准质量标签。信号质量基于两种方案进行分类:二进制分类(“不可接受”和“可接受”)和三重分类(“不可接受”、“良好”和“优秀”)。顺序前向特征选择表明,特征“周期性程度”在二进制 SVM 分类中的准确率为 73.1%。前五个特征主导分类性能,准确率为 92%。由于准确率达到(90.4±0.5)%,即使使用 10%的数据来训练分类器,二进制分类器也具有出色的泛化能力。在 10 倍验证中,准确率提高到(94.3±0.7)%。三重分类在 10 倍验证中的准确率为(85.7±0.6)%。结果验证了信号质量评估的有效性,它可以作为未来临床应用中自动心音分析的预处理方法之一。