Knuuttila M L, Paunio K U, Mielityinen H
J Periodontol. 1978 Feb;49(2):96-101. doi: 10.1902/jop.1978.49.2.96.
The effects of chlorhexidine on the appearance of leukocytes and some hydrolytic enzymes were studied in an experimental acute nonmicrobial inflammation reaction caused by implanation of viscose sponge beneath the backskin. The results showed that chlorhexidine gluconate decreased the number of leukocytes in the inflammatory exudate. The drug used had no measurable effect on the distribution of different types of leukocytes. Chlorhexidine has a clear inhibitory effect on the appearance of phosphatases, glycosidases and peptidases. On the other hand the effect on proteinases was small.
在背部皮肤下植入粘胶海绵引发的实验性急性非微生物炎症反应中，研究了洗必泰对白细胞外观及一些水解酶的影响。结果表明，葡萄糖酸氯己定可减少炎性渗出物中白细胞的数量。所用药物对不同类型白细胞的分布没有可测量的影响。洗必泰对磷酸酶、糖苷酶和肽酶的出现有明显的抑制作用。另一方面，对蛋白酶的影响较小。
