在一项针对牙周病患者的纵向研究中，牙齿数量可预测抑郁症状。

Number of teeth predict depressive symptoms in a longitudinal study on patients with periodontal disease.

作者信息

Ehrenthal Johannes C, Graetz Christian, Plaumann Anna, Dörfer Christof E, Herzog Wolfgang

机构信息

Department of General Internal Medicine and Psychosomatics, Heidelberg University, Germany; Department of Psychology, University of Kassel, Germany.

Department of Conservative Dentistry and Periodontology, University of Kiel, Germany.

出版信息

J Psychosom Res. 2016 Oct;89:16-9. doi: 10.1016/j.jpsychores.2016.08.002. Epub 2016 Aug 4.

DOI:10.1016/j.jpsychores.2016.08.002

PMID:27663105

Abstract

OBJECTIVE

Periodontal disease is associated with a wide range of psychosocial risk-factors. Disease-related tooth-loss has been associated with an increase in depressive symptoms in cross-sectional studies. However, while depression is a known risk-factor for the outcome of chronic diseases, it remains unclear if tooth loss can also predict depressive symptoms over the course of treatment. Aim of the current pilot study was to test, to what extend the number of teeth predict depressive symptoms several years later.

METHODS

Tooth status of 310 patients with chronic and aggressive periodontitis was evaluated at the beginning of a specialized, university based outpatient treatment. We assessed depressive symptoms with the Patient Heath Questionnaire (PHQ) on average 13years later. Regression analyses were used to relate initial number of teeth to self-reported depression scores.

RESULTS

Fewer teeth at the beginning of the treatment were related to higher scores of depressive symptoms, even when controlling for several covariates.

CONCLUSIONS

Tooth loss is a potential risk-factor for the development of depression in periodontal disease. Further longitudinal studies that control for initial depressive symptoms are needed to identify disease mechanisms.

摘要