Das Jai K, Salam Rehana A, Lassi Zohra S, Khan Marium Naveed, Mahmood Wajeeha, Patel Vikram, Bhutta Zulfiqar A
Division of Women and Child Health, Aga Khan University, Karachi, Pakistan.
Robinson Research Institute, University of Adelaide, Adelaide, Australia.
J Adolesc Health. 2016 Oct;59(4S):S49-S60. doi: 10.1016/j.jadohealth.2016.06.020.
Many mental health disorders emerge in late childhood and early adolescence and contribute to the burden of these disorders among young people and later in life. We systematically reviewed literature published up to December 2015 to identify systematic reviews on mental health interventions in adolescent population. A total of 38 systematic reviews were included. We classified the included reviews into the following categories for reporting the findings: school-based interventions (n = 12); community-based interventions (n = 6); digital platforms (n = 8); and individual-/family-based interventions (n = 12). Evidence from school-based interventions suggests that targeted group-based interventions and cognitive behavioral therapy are effective in reducing depressive symptoms (standard mean difference [SMD]: -.16; 95% confidence interval [CI]: -.26 to -.05) and anxiety (SMD: -.33; 95% CI: -.59 to -.06). School-based suicide prevention programs suggest that classroom-based didactic and experiential programs increase short-term knowledge of suicide (SMD: 1.51; 95% CI: .57-2.45) and knowledge of suicide prevention (SMD: .72; 95% CI: .36-1.07) with no evidence of an effect on suicide-related attitudes or behaviors. Community-based creative activities have some positive effect on behavioral changes, self-confidence, self-esteem, levels of knowledge, and physical activity. Evidence from digital platforms supports Internet-based prevention and treatment programs for anxiety and depression; however, more extensive and rigorous research is warranted to further establish the conditions. Among individual- and family-based interventions, interventions focusing on eating attitudes and behaviors show no impact on body mass index (SMD: -.10; 95% CI: -.45 to .25); Eating Attitude Test (SMD: .01; 95% CI: -.13 to .15); and bulimia (SMD: -.03; 95% CI: -.16 to .10). Exercise is found to be effective in improving self-esteem (SMD: .49; 95% CI: .16-.81) and reducing depression score (SMD: -.66; 95% CI: -1.25 to -.08) with no impact on anxiety scores. Cognitive behavioral therapy compared to waitlist is effective in reducing remission (odds ratio: 7.85; 95% CI: 5.31-11.6). Psychological therapy when compared to antidepressants have comparable effect on remission, dropouts, and depression symptoms. The studies evaluating mental health interventions among adolescents were reported to be very heterogeneous, statistically, in their populations, interventions, and outcomes; hence, meta-analysis could not be conducted in most of the included reviews. Future trials should also focus on standardized interventions and outcomes for synthesizing the exiting body of knowledge. There is a need to report differential effects for gender, age groups, socioeconomic status, and geographic settings since the impact of mental health interventions might vary according to various contextual factors.
许多心理健康障碍在儿童晚期和青少年早期出现,并加重了年轻人及之后生活中这些障碍的负担。我们系统回顾了截至2015年12月发表的文献,以确定关于青少年心理健康干预措施的系统评价。共纳入38项系统评价。我们将纳入的评价分为以下几类以报告研究结果:基于学校的干预措施(n = 12);基于社区的干预措施(n = 6);数字平台(n = 8);以及基于个体/家庭的干预措施(n = 12)。基于学校的干预措施的证据表明,有针对性的小组干预措施和认知行为疗法在减轻抑郁症状(标准均数差[SMD]:-.16;95%置信区间[CI]:-.26至-.05)和焦虑(SMD:-.33;95%CI:-.59至-.06)方面是有效的。基于学校的自杀预防项目表明,基于课堂的讲授式和体验式项目可增加自杀的短期知识(SMD:1.51;95%CI:.57 - 2.45)以及自杀预防知识(SMD:.72;95%CI:.36 - 1.07),但没有证据表明对与自杀相关的态度或行为有影响。基于社区的创意活动对行为改变、自信心、自尊、知识水平和身体活动有一些积极影响。来自数字平台的证据支持基于互联网的焦虑和抑郁预防及治疗项目;然而,需要更广泛和严格的研究来进一步确定相关条件。在基于个体和家庭的干预措施中,关注饮食态度和行为的干预措施对体重指数(SMD:-.10;95%CI:-.45至.25)、饮食态度测试(SMD:.01;95%CI:-.13至.15)和贪食症(SMD:-.03;95%CI:-.16至.10)没有影响。发现运动在提高自尊(SMD:.49;95%CI:.16 -.81)和降低抑郁评分(SMD:-.66;95%CI:-1.25至-.08)方面有效,但对焦虑评分没有影响。与等待名单相比,认知行为疗法在减少缓解期方面有效(优势比:7.85;95%CI:5.31 - 11.6)。与抗抑郁药相比,心理治疗在缓解期、退出率和抑郁症状方面有相当的效果。据报道,评估青少年心理健康干预措施时,在人群、干预措施和结果方面,各项研究在统计学上差异很大;因此,在大多数纳入的评价中无法进行荟萃分析。未来的试验还应侧重于标准化的干预措施和结果,以整合现有的知识体系。由于心理健康干预措施的影响可能因各种背景因素而异,有必要报告不同性别、年龄组、社会经济地位和地理环境的差异效应。