南部非洲的白化病与皮肤癌
Albinism and skin cancer in Southern Africa.
作者信息
Kromberg J G, Castle D, Zwane E M, Jenkins T
机构信息
Department of Human Genetics, School of Pathology, South African Institute for Medical Research.
出版信息
Clin Genet. 1989 Jul;36(1):43-52. doi: 10.1111/j.1399-0004.1989.tb03365.x.
The presence of skin cancer was investigated in 111 albinos belonging to the black (Negro) population of Johannesburg, South Africa. The overall rate was 23.4%, the risk increasing with age. Identifiable risk factors included: environmental exposure to ultraviolet radiation; inability to produce ephelides ('freckles'); and possibly ethnicity. The head was the site most commonly affected, and squamous was far more common than basal cell carcinoma. No melanomas were detected. Recommendations are made regarding prevention of skin cancer in the at-risk group.
对南非约翰内斯堡黑人（尼格罗人）群体中的111名白化病患者进行了皮肤癌患病情况调查。总体发病率为23.4%，风险随年龄增长而增加。可识别的风险因素包括：环境中紫外线辐射暴露；无法产生雀斑；以及可能的种族因素。头部是最常受影响的部位，鳞状细胞癌远比基底细胞癌常见。未检测到黑色素瘤。针对高危人群的皮肤癌预防提出了建议。
Zotero 插件