从低亲和力到高亲和力的单分子表面反应的原位观察。
In Situ Observation of Single-Molecule Surface Reactions from Low to High Affinities.
机构信息
Max Planck Institute for the Science of Light, Günther-Scharowsky-Straβe 1, 91058, Erlangen, Germany.
出版信息
Adv Mater. 2016 Dec;28(45):9941-9948. doi: 10.1002/adma.201603153. Epub 2016 Sep 28.
In situ observation of single-molecule surface reactions from low to high affinities is achieved by resonant coupling between optical whispering-gallery modes and the localized surface plasmon of nanorods. Transient and permanent interactions between ligands (thiol, amine) and the gold surface are monitored without labels, allowing direct determination of the associated kinetic constants and rapid development of new functionalization protocols.
通过光学 whispering-gallery 模式与纳米棒的局域表面等离激元之间的共振耦合，实现了从低亲和力到高亲和力的单分子表面反应的原位观察。在无需标记的情况下监测配体（硫醇、胺）与金表面的瞬态和永久相互作用，允许直接确定相关的动力学常数，并快速开发新的功能化方案。
Zotero 插件