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不同外科疾病中幽门螺杆菌的患病率:初步报告。

Prevalence of Helicobacter Pylori in Different Surgical Diseases: A Preliminary Report.

作者信息

Ilic Mirka, Popovic Nada

机构信息

Center for Medical Biochemistry, Clinical Center of Serbia , Belgrade, Serbia.

Department of Anesthesiology and Emergency Surgery, Medical School of Belgrade-University of Belgrade & Clinical Center of Serbia , Belgrade, Serbia.

出版信息

EJIFCC. 2011 Dec 22;22(4):109-12. eCollection 2011 Dec.

Abstract

The aim of this study was to explore the prevalence of Helicobacter pylori infection in different surgical diseases in patients with six different cancer types. We analyzed sixty consecutive patients with malignancy (gastric cancer, pancreatic cancer, hepatocellular cancer, intestinal cancer, colon cancer, rectal cancer). Detection of specific IgA and IgG antibodies to Helicobacter pylori in human serum was determined by Enzygnost Anti-Helicobacter pylori II/IgA (IgG) using ELISA processor (Siemens, Germany). This study confirmed statistically significant association between Helicobacter pylori seropositivity and all types of cancer included in the study. All patients had elevated levels of Helicobacter pylori IgA and IgG antibodies. Patients with examined cancer types that underwent abdominal surgery exibited a strong antibody reaction to Helicobacter pylori.

摘要

本研究的目的是探讨六种不同癌症类型患者中不同外科疾病的幽门螺杆菌感染率。我们分析了60例连续的恶性肿瘤患者(胃癌、胰腺癌、肝细胞癌、小肠癌、结肠癌、直肠癌)。使用酶联免疫分析仪(德国西门子公司),通过酶免疫法抗幽门螺杆菌II/IgA(IgG)检测人血清中幽门螺杆菌特异性IgA和IgG抗体。本研究证实,幽门螺杆菌血清阳性与研究中纳入的所有癌症类型之间存在统计学上的显著关联。所有患者的幽门螺杆菌IgA和IgG抗体水平均升高。接受腹部手术的受检癌症类型患者对幽门螺杆菌表现出强烈的抗体反应。

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