利用皮下腹部脂肪活检标本通过氨基酸序列分析对淀粉样纤维蛋白AL进行详细分型。
Use of subcutaneous abdominal fat biopsy specimen for detailed typing of amyloid fibril protein-AL by amino acid sequence analysis.
作者信息
Westermark P, Benson L, Juul J, Sletten K
机构信息
Department of Pathology, University of Linköping, Sweden.
出版信息
J Clin Pathol. 1989 Aug;42(8):817-9. doi: 10.1136/jcp.42.8.817.
Abstract
A simple technique for the purification of amyloid fibril proteins from patients with systemic amyloidosis was used on a 45 year old woman. The method is based on the use of a surgical subcutaneous fat tissue biopsy specimen which was used for the characterisation of the amyloid as a kappa I AL-protein by amino acid sequence analysis. The method permits the exact typing of amyloid in many patients with systemic amyloidosis, which, until now has been almost exclusively confined to necropsy tissue.
摘要
一种从系统性淀粉样变性患者中纯化淀粉样纤维蛋白的简单技术应用于一名45岁女性。该方法基于使用手术获取的皮下脂肪组织活检标本，通过氨基酸序列分析将淀粉样蛋白鉴定为κI AL蛋白。该方法能对许多系统性淀粉样变性患者的淀粉样蛋白进行准确分型，而在此之前，这几乎完全局限于尸检组织。
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2
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3
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4
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6
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