• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

实验性鼠疫杆菌感染小鼠期间，原发灶中多形核白细胞和巨噬细胞氧依赖代谢活性的变化。

Changes in the activity of oxygen-dependent metabolism in polymorphonuclear leukocytes and macrophages from a primary focus during experimental Y. pestis infection in the mouse.

作者信息

Isin Z M

机构信息

Central Asia Anti-Plague Research Institute, Alma-Ata, USSR.

出版信息

J Hyg Epidemiol Microbiol Immunol. 1989;33(2):229-32.

PMID:2768822
Abstract

The activity of oxygen-dependent metabolism (OM) was investigated in phagocytosing cells from a primary focus in plague infection using a mouse model. Experimental animals were given various i.p. doses of a virulent culture of Y. pestis. Changes in the OM of neutrophils and macrophages derived from peritoneal exudate after Y. pestis administration were phased and identical to non-specific post-aggression fluctuating reaction (PFR) comprising: 1. immediate depression phase, 2. overexertion phase and 3. exhaustion phase.

摘要

使用小鼠模型，对来自鼠疫感染原发病灶的吞噬细胞中氧依赖性代谢（OM）的活性进行了研究。给实验动物腹腔注射不同剂量的鼠疫耶尔森氏菌强毒株培养物。注射鼠疫耶尔森氏菌后，腹膜渗出液中中性粒细胞和巨噬细胞的OM变化呈阶段性，与非特异性攻击后波动反应（PFR）相同，包括：1. 即刻抑制期，2. 过度劳累期和3. 疲惫期。

相似文献

1
Changes in the activity of oxygen-dependent metabolism in polymorphonuclear leukocytes and macrophages from a primary focus during experimental Y. pestis infection in the mouse.实验性鼠疫杆菌感染小鼠期间，原发灶中多形核白细胞和巨噬细胞氧依赖代谢活性的变化。
J Hyg Epidemiol Microbiol Immunol. 1989;33(2):229-32.
2
[Changes in the oxygen-dependent metabolic activity of polymorphonuclear leukocytes from the peripheral blood and macrophages from the peritoneal exudate in the experimental infection of mice with the causative agent of plague].[鼠疫病原体实验感染小鼠时外周血多形核白细胞和腹腔渗出液巨噬细胞氧依赖性代谢活性的变化]
Zh Mikrobiol Epidemiol Immunobiol. 1985 Oct(10):69-76.
3
[Changes in the antimicrobial potential of the phagocytosing cells of great gerbils in experimental plague].[实验性鼠疫中长爪沙鼠吞噬细胞抗菌潜能的变化]
Zh Mikrobiol Epidemiol Immunobiol. 1987 Nov(11):84-8.
4
Enhancement of host defence by Y-19995 (2,4'-bis(1-methyl-2-dimethyl-aminoethoxyl)-3-benzoylpyridine dimaleate), a novel synthetic compound. II. Activation of phagocytic cell functions.新型合成化合物Y-19995（2,4'-双（1-甲基-2-二甲基氨基乙氧基）-3-苯甲酰吡啶二马来酸酯）对宿主防御功能的增强作用。II. 吞噬细胞功能的激活
J Clin Lab Immunol. 1987 Dec;24(4):177-81.
5
Neutralization of Yersinia pestis-mediated macrophage cytotoxicity by anti-LcrV antibodies and its correlation with protective immunity in a mouse model of bubonic plague.抗LcrV抗体对鼠疫耶尔森菌介导的巨噬细胞细胞毒性的中和作用及其与腺鼠疫小鼠模型中保护性免疫的相关性。
Vaccine. 2008 Mar 20;26(13):1616-25. doi: 10.1016/j.vaccine.2008.01.033. Epub 2008 Feb 6.
6
[Adenylate cyclase. A possible factor in the pathogenicity of Yersinia pestis].[腺苷酸环化酶。鼠疫耶尔森菌致病性的一个可能因素]
Bull Soc Pathol Exot. 1992;85(1):17-21.
7
[The cell morphology of peritoneal exudate in the course of bacterial peritonitis (experimental animal studies)].
Z Exp Chir Transplant Kunstliche Organe. 1988;21(6):313-21.
8
Comparative investigation of PMN leucocyte antimicrobial potential in animals of different species susceptibility to the plague agent.
J Hyg Epidemiol Microbiol Immunol. 1987;31(3):307-12.
9
Superoxide release by peritoneal and bone marrow-derived mouse macrophages. Modulation by adherence and cell activation.腹膜和骨髓来源的小鼠巨噬细胞释放超氧化物。黏附与细胞激活的调节作用。
Immunology. 1983 Aug;49(4):693-704.
10
[Inflammatory reaction to polyester threads in guinea pigs. III. Reduction of Nitroblue tetrazolium by peritoneal macrophages in vitro].[豚鼠对聚酯线的炎症反应。III. 体外腹腔巨噬细胞对硝基蓝四氮唑的还原作用]
Boll Soc Ital Biol Sper. 1980 Jun 15;56(11):1144-9.