多聚磷酸盐的多种面貌。
PolyP's many faces.
作者信息
Schmaier Alvin H
机构信息
UNIVERSITY HOSPITALS CASE MEDICAL CENTER; CASE WESTERN RESERVE UNIVERSITY.
出版信息
Blood. 2016 Sep 29;128(13):1669-70. doi: 10.1182/blood-2016-07-724971.
Abstract
In this issue of , Wijeyewickrema et al present the novel finding that polyphosphate (polyP) functions as a cofactor to C1-esterase inhibitor (C1-INH) inhibition of the enzyme C1s in the first component of the macromolecular structure of C1.
摘要
在本期《 》中，维杰维克勒马等人提出了一项新发现，即多聚磷酸盐（polyP）作为一种辅助因子，可协助C1酯酶抑制剂（C1-INH）对C1大分子结构第一成分中的C1s酶进行抑制。
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本文引用的文献
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Polyphosphate is a novel cofactor for regulation of complement by a serpin, C1 inhibitor.多聚磷酸盐是丝氨酸蛋白酶抑制剂C1抑制剂调节补体的一种新型辅助因子。
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Single-chain factor XII exhibits activity when complexed to polyphosphate.单链因子 XII 与多聚磷酸盐结合时具有活性。
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Polyphosphate exerts differential effects on blood clotting, depending on polymer size.聚磷酸盐对凝血的影响因聚合物大小而异。
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