Schmaier Alvin H
UNIVERSITY HOSPITALS CASE MEDICAL CENTER; CASE WESTERN RESERVE UNIVERSITY.
Blood. 2016 Sep 29;128(13):1669-70. doi: 10.1182/blood-2016-07-724971.
In this issue of , Wijeyewickrema et al present the novel finding that polyphosphate (polyP) functions as a cofactor to C1-esterase inhibitor (C1-INH) inhibition of the enzyme C1s in the first component of the macromolecular structure of C1.
在本期《 》中,维杰维克勒马等人提出了一项新发现,即多聚磷酸盐(polyP)作为一种辅助因子,可协助C1酯酶抑制剂(C1-INH)对C1大分子结构第一成分中的C1s酶进行抑制。