Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University , Beijing 100084, China.
Org Lett. 2016 Oct 21;18(20):5248-5251. doi: 10.1021/acs.orglett.6b02553. Epub 2016 Sep 30.
Efficient and practical visible-light photoredox borylation of aryl halides and subsequent aerobic oxidative hydroxylation were developed. The protocols use readily available aryl halides and bis(pinacolato)diboron as the starting materials, fac-Ir(ppy) as the photocatalyst, and corresponding arylboronic esters and phenols were obtained in good yields. The methods show some advantages including simple equipment, mild conditions, easy operation, and wide substrate scope. Therefore, they should provide a valuable strategy for chemical transformations.
开发了高效实用的可见光光氧化还原硼化芳基卤化物及随后的有氧氧化羟基化反应。该方案使用易得的芳基卤化物和联硼酸频哪醇酯作为起始原料，fac-Ir(ppy)作为光催化剂，以较好的产率得到相应的芳基硼酸酯和苯酚。该方法具有设备简单、条件温和、操作方便、底物范围广等优点。因此，它们应该为化学转化提供一种有价值的策略。
