Balevi Ali, Üstüner Pelin, Özdemir Mustafa
a School of Medicine, Department of Dermatology , Istanbul Medipol University , Istanbul , Turkey.
J Dermatolog Treat. 2017 Jun;28(4):368-371. doi: 10.1080/09546634.2016.1244601. Epub 2016 Oct 24.
Recalcitrant facial verruca plana (FVP) may persist for years and full remission is not always achieved with conventional therapies. The clinical success rates reported for different lasers are highly variable and only one study evaluated the Er:YAG laser for the treatment of FVP.
To determine whether Er:YAG is safe and effective for the treatment of recalcitrant FVP.
Forty-six patients with recalcitrant FVP were treated by Er:YAG at four-week intervals. The patients' clinical response, adverse effects such as scarring and pigment change, recurrence and patient satisfaction were assessed. Patients were clinically evaluated after each session over a six-month follow-up.
A total of 550 lesions of 46 participants were treated with 1-3 passes. The patients received 1-4 laser sessions with one session on average. Thirty-two patients (62.5%) achieved a complete response with 458 lesions (83.3%) being completely and 30 (5.5%) being partially healed. The post-treatment side effects were post-inflammatory hyperpigmentation and mild scar formation. FVP recurred in 12 patients (26.0%). Twenty-six patients (56.5%) were completely satisfied and nine (19.5%) were mostly satisfied with the treatment.
Er:YAG laser is a good treatment option in patients with recalcitrant FVP, particularly for cosmetically sensitive areas.
顽固性扁平疣（FVP）可能持续数年，传统疗法并不总能实现完全缓解。不同激光治疗报告的临床成功率差异很大，仅有一项研究评估了铒激光（Er:YAG）治疗FVP。
确定Er:YAG治疗顽固性FVP是否安全有效。
46例顽固性FVP患者接受Er:YAG治疗，间隔四周一次。评估患者的临床反应、诸如瘢痕形成和色素改变等不良反应、复发情况及患者满意度。在六个月的随访期内，每次治疗后对患者进行临床评估。
46名参与者共550个皮损接受了1 - 3次照射。患者接受了1 - 4次激光治疗，平均每人1次。32例患者（62.5%）获得完全缓解，458个皮损（83.3%）完全愈合，30个（5.5%）部分愈合。治疗后的副作用为炎症后色素沉着和轻度瘢痕形成。12例患者（26.0%）出现FVP复发。26例患者（56.5%）对治疗完全满意，9例（19.5%）基本满意。
Er:YAG激光是治疗顽固性FVP患者的良好选择，尤其适用于对美容敏感的区域。
