Shrestha S, Karn D
Department of Dermatology, Kathmandu University School of Medical Sciences, Dhulikhel, Kavre, Nepal.
Kathmandu Univ Med J (KUMJ). 2018;16(61):60-64.
Background Despite multiple treatment options, there is no consensus on a particular treatment modality in warts. Previous studies have reported safety and efficacy of long-pulsed Neodymium-doped yttrium aluminium garnet (Nd:YAG) laser, with clearance rates higher than those achieved with other therapies. This study was designed to evaluate the efficacy of long-pulsed Nd:YAG laser in the treatment of warts in Nepal. Objective To assess the efficacy of Long pulsed Nd:YAG in the management of verruca vulgaris. Method Fourty cases of common warts over hands and feet were enrolled in the study. Patients with less than 10 lesions were chosen. Up to three sessions of 1064 nm Long pulse Nd:YAG treatment were done, at the interval of one month. No concomitant topical or other treatment was done. Result Out of the 40 patients, four patients were lost to follow up. Among 36 patients, eight patients (22%) achieved clearance of warts in single session, while 12 (33%) patients and six patients (16%) improved after second and third sessions of laser respectively. Hence, we observed 72% clearance rate after three sessions of lasers. Adverse effects were pain during treatment and scarring in few patients. Conclusion Long pulse Nd:YAG is effective in the treatment of verruca. However, pain and tissue damage are the limitations. Hence, we suggest that Long Pulsed Nd:YAG lasers are effective in recalcitrant cutaneous and palmoplantar warts.
尽管有多种治疗选择,但对于疣的特定治疗方式尚无共识。先前的研究报道了长脉冲掺钕钇铝石榴石(Nd:YAG)激光的安全性和有效性,其清除率高于其他疗法。本研究旨在评估长脉冲Nd:YAG激光治疗尼泊尔疣的疗效。
评估长脉冲Nd:YAG激光治疗寻常疣的疗效。
本研究纳入了40例手足部寻常疣患者。选择皮损少于10个的患者。进行了多达3次1064nm长脉冲Nd:YAG治疗,间隔1个月。未进行其他局部或其他治疗。
40例患者中,4例失访。在36例患者中,8例(22%)单次治疗后疣清除,12例(33%)和6例(16%)患者分别在第二次和第三次激光治疗后病情改善。因此,三次激光治疗后我们观察到清除率为72%。不良反应为治疗期间疼痛和少数患者出现瘢痕形成。
长脉冲Nd:YAG激光治疗疣有效。然而,疼痛和组织损伤是其局限性。因此,我们建议长脉冲Nd:YAG激光对顽固性皮肤和掌跖疣有效。