Center for Complex Networks Research, Northeastern University, Boston, MA 02115, USA; Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
GeneTAG Technology, Inc., Atlanta, GA 30340, USA.
Trends Mol Med. 2016 Nov;22(11):919-921. doi: 10.1016/j.molmed.2016.09.006. Epub 2016 Sep 28.
To date, no antiviral agents have been approved for treating Zika virus (ZIKV) infection. Two recent drug-repurposing studies published in Cell Host & Microbe and Nature Medicine demonstrated that screening FDA-approved drugs for antiviral activity is a promising strategy for identifying therapeutics with novel activity against ZIKV infection.
迄今为止,尚无抗病毒药物获批用于治疗寨卡病毒(ZIKV)感染。最近在《Cell Host & Microbe》和《Nature Medicine》上发表的两项药物再利用研究表明,筛选美国食品药品监督管理局(FDA)批准的药物的抗病毒活性是一种很有前途的策略,可以鉴定出针对 ZIKV 感染具有新型活性的治疗药物。