Segbedji K A R, Djadou K E, Tchagbele O-B, Kpegouni M, Bessi Kama L K, Azoumah K D, Agbèrè A D
Département de pédiatrie, FSS-UK, CHU-K , BP 18, Kara, Togo.
Département de Pédiatrie, CHR-Tsévié, FSS-UL, BP 57, Lomé, Togo.
Med Sante Trop. 2016 Aug 1;26(3):318-322. doi: 10.1684/mst.2016.0593.
Tuberculosis (TB) remains one of the most lethal communicable diseases in the world, according to the World Health Organization (WHO). New strategies must be implemented to meet targets for 2035.
Describe the epidemiological and therapeutic aspects of tuberculosis in children in Togo.
This retrospective, multicenter, descriptive cross-sectional study examined the files of children younger than 15 years who were diagnosed with TB and treatment in the Maritime region from 2008 to 2011.
The study included 74 children aged 0-15 years, for an average of 18 cases of childhood tuberculosis annually. Pulmonary tuberculosis (38 cases) was the most common. TB-HIV co-infection was found in 14.9% of cases. Boys accounted for more than half of the patients. The age range of 11-15 years accounted for the highest proportion of cases (41.9%). The most common treatment was a combination of 2RHZE and 4RH (25 children, 33.8%). Laboratory monitoring was satisfactory. In all, 56 (75.7%) children were cured, and 14 (18.2%) lost to follow-up, while 3 (4%) died (all with TB/HIV).
Active testing for HIV infection is essential in children with TB, because the combination of the two can be lethal.
根据世界卫生组织（WHO）的数据，结核病（TB）仍然是世界上最致命的传染病之一。必须实施新战略以实现2035年的目标。
描述多哥儿童结核病的流行病学和治疗方面。
这项回顾性、多中心、描述性横断面研究检查了2008年至2011年在滨海区被诊断患有结核病并接受治疗的15岁以下儿童的档案。
该研究纳入了74名0至15岁的儿童，平均每年有18例儿童结核病病例。肺结核（38例）最为常见。14.9%的病例发现有结核与艾滋病病毒合并感染。男孩占患者的一半以上。11至15岁年龄组的病例比例最高（41.9%）。最常用的治疗方法是2RHZE和4RH联合治疗（25名儿童，33.8%）。实验室监测情况良好。共有56名（75.7%）儿童治愈，14名（18.2%）失访，3名（4%）死亡（均为结核与艾滋病病毒合并感染）。
对结核病儿童进行艾滋病病毒感染的主动检测至关重要，因为二者合并感染可能是致命的。
