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[尼日尔共和国马拉迪地区医院结核病患者的流行病学、临床和演变情况]

[Epidemiological, clinical and evolutionary profile of patients with tuberculosis at the Regional Hospital of Maradi, Republic of the Niger].

作者信息

Amadou Mahaman Laouali Harouna, Abdoulaye Ousmane, Amadou Oumarou, Biraïma Ahamadou, Kadri Sani, Amoussa Abdoul Aziz Kabiru, Lawan Ibrahim Maman, Tari Laouali, Daou Maman, Brah Souleymane, Adehossi Eric

机构信息

Service d'Infectiologie, Hôpital Régional de Maradi, Faculté des Sciences de la Santé de l'Université de Maradi, Maradi, Niger.

Service de Biologie Médicale, Hôpital Régional de Maradi, Faculté des Sciences de la Santé de l'Université de Maradi, Maradi, Niger.

出版信息

Pan Afr Med J. 2019 Jun 17;33:120. doi: 10.11604/pamj.2019.33.120.17715. eCollection 2019.

Abstract

INTRODUCTION

This study aimed to describe the epidemiological, clinical and evolutionary profile of patients treated for tuberculosis at the Regional Hospital of Maradi.

METHODS

We conducted a retrospective, descriptive and analytical study of data from the medical records of patients treated for tuberculosis from 1 January 2015 to 31 December 2017.

RESULTS

A total of 595 patients were followed (406 men, 68.24%, and 189 women, 31.76%) with a prevalence of 27,71%. The average age of patients was 42.3 ranging from 13 months to 85 years; 70.5% of these patients were from urban areas. Merchants represented 36.9% of the cases. Bacterial test was positive in 64.7% of cases. Functional signs included: coughing (99.5%), fever (79.5%), and chest pain. Pulmonary tuberculosis represented 78.7% of cases. Therapy was effective in 81.28% of cases. HIV prevalence was 13.6%, lethality 10.42% (40.4% of patients died from TB/HIV co-infection).

CONCLUSION

Tuberculosis is a scourge in low-income countries, with 10.42% of deaths. HIV/AIDS infection has negatively contributed to these deaths during the study period. The search for comorbidities in any patient with tuberculosis should be systematic in order to improve their global management.

摘要

引言

本研究旨在描述在马拉迪地区医院接受结核病治疗的患者的流行病学、临床和病情演变情况。

方法

我们对2015年1月1日至2017年12月31日期间接受结核病治疗的患者病历数据进行了一项回顾性、描述性和分析性研究。

结果

共对595名患者进行了随访(406名男性,占68.24%;189名女性,占31.76%),患病率为27.71%。患者的平均年龄为42.3岁,年龄范围从13个月至85岁;其中70.5%的患者来自城市地区。商人占病例的36.9%。细菌检测阳性率为64.7%。功能症状包括:咳嗽(99.5%)、发热(79.5%)和胸痛。肺结核占病例的78.7%。治疗有效率为81.28%。艾滋病毒感染率为13.6%,致死率为10.42%(40.4%的患者死于结核病/艾滋病毒合并感染)。

结论

结核病在低收入国家是一场灾难,致死率为10.42%。在研究期间,艾滋病毒/艾滋病感染对这些死亡产生了负面影响。对任何结核病患者进行合并症筛查都应系统进行,以改善其整体治疗。

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