Hervonen A, Linnoila I, Vaalasti A, Alho H, Pelto-Huikko M
Department of Public Health, Tampere Brain Research Center, University of Tampere, Finland.
J Electron Microsc Tech. 1989 Aug;12(4):380-8. doi: 10.1002/jemt.1060120410.
Enkephalin-like immunoreactivity in human adrenomedullary cells was studied at the light and electron microscopic levels. Enkephalin immunostaining was associated with chromaffin granules and, in a few cells, with the rough endoplasmic reticulum as well. The relative number of stained granules varied from cell to cell, and a correlation with a particular granular population was not noted. Both large and small granules were labelled. It is concluded that in the human the ability to store enkephalin immunoreactive peptides is a general property of chromaffin granules and, furthermore, is not correlated with specific granular subpopulations or the particular type of catecholamine stored within the cell.
在光学显微镜和电子显微镜水平上研究了人肾上腺髓质细胞中脑啡肽样免疫反应性。脑啡肽免疫染色与嗜铬颗粒有关，在少数细胞中也与粗面内质网有关。染色颗粒的相对数量因细胞而异，未发现与特定颗粒群体有相关性。大颗粒和小颗粒均被标记。得出的结论是，在人类中，储存脑啡肽免疫反应性肽的能力是嗜铬颗粒的一般特性，此外，与特定的颗粒亚群或细胞内储存的特定儿茶酚胺类型无关。
