Merwald-Fraenk H, Wiesent F, Dörfler R, Goebel C
Endokrinologikum München, Promenadeplatz 12, 80333, München, Deutschland.
Klinikum München - Bogenhausen, Klinik für Rheumatologie und Klinische Immunologie, Lehrkrankenhaus, Technische Universität München, München, Deutschland.
Z Rheumatol. 2016 Dec;75(10):1028-1031. doi: 10.1007/s00393-016-0170-7.
A 25-year-old Caucasian female patient presented with fever and cervical lymphadenopathy. Laboratory findings showed elevated signs of inflammation, elevated ANA titer and strongly positive anti-dsDNA antibodies. The histopathology of the lymph nodes revealed distinct features of Kikuchi-Fujimoto disease, a benign, self-limiting lymphadenopathy that typically affects young Asian females. In the literature a coincidental occurrence of Kikuchi-Fujimoto disease and systemic lupus erythematosus (SLE) is well documented. We hypothesized a simultaneous occurrence of both diseases because of the typical antibodies and arthralgia.
一名25岁的白种女性患者出现发热和颈部淋巴结病。实验室检查结果显示炎症指标升高、抗核抗体滴度升高以及抗双链DNA抗体强阳性。淋巴结的组织病理学显示了菊池-藤本病的典型特征,这是一种良性、自限性淋巴结病,通常影响年轻亚洲女性。文献中已充分记录了菊池-藤本病与系统性红斑狼疮(SLE)的巧合发生。由于典型的抗体和关节痛,我们推测这两种疾病同时发生。