Hamilton Jessica L, Alloy Lauren B
Temple University, Department of Psychology, 1701 N. 13th St., Philadelphia, PA 19122, United States.
Temple University, Department of Psychology, 1701 N. 13th St., Philadelphia, PA 19122, United States.
Clin Psychol Rev. 2016 Dec;50:67-79. doi: 10.1016/j.cpr.2016.09.003. Epub 2016 Sep 20.
Heart rate variability has received growing attention in the depression literature, with several recent meta-analyses indicating that lower resting heart rate variability is associated with depression. However, the role of fluctuations in heart rate variability (or reactivity) in response to stress in depression remains less clear. The present review provides a systematic examination of the literature on heart rate variability reactivity to a laboratory-induced stressor task and depression, including 26 studies of reactivity in heart rate variability and clinical depression, remitted (or history of) depression, and subthreshold depression (or symptom-level depression) among adults, adolescents, and children. In addition to reviewing the findings of these studies, methodological considerations and conceptual gaps in the literature are addressed. We conclude by highlighting the importance of investigating the potential transactional relationship between heart rate variability reactivity and depression and possible mechanisms underlying this relationship.
心率变异性在抑郁症文献中受到越来越多的关注，最近的几项荟萃分析表明，静息心率变异性较低与抑郁症有关。然而，心率变异性波动（或反应性）在抑郁症应激反应中的作用仍不太明确。本综述对心率变异性对实验室诱发应激源任务的反应性与抑郁症的文献进行了系统研究，包括26项关于成年人、青少年和儿童心率变异性反应性与临床抑郁症、缓解期（或有抑郁症病史）和阈下抑郁症（或症状级抑郁症）的研究。除了回顾这些研究的结果外，还讨论了文献中的方法学考虑因素和概念空白。我们强调研究心率变异性反应性与抑郁症之间潜在的相互作用关系以及这种关系背后可能机制的重要性，以此作为结论。
