O'Gallagher Kevin, Chou Evelyn, Jeyabraba Swarna, Sinha Aish, Robb Daniel, Byrne Jonathan
specialty registrar in interventional cardiology, King's College Hospital NHS Foundation Trust, London, UK
medical student, King's College School of Medical Education, King's College London, London, UK.
Clin Med (Lond). 2016 Oct;16(5):453-454. doi: 10.7861/clinmedicine.16-5-453.
An 80-year-old female presented with progressive breathlessness, worse on sitting or standing and relieved by lying flat. Subsequent investigations identified a patent foramen ovale (PFO) with right-to-left flow across the interatrial septum (IAS). A diagnosis of platypnoea orthodeoxia syndrome secondary to inter-atrial shunting was made. Technical features precluded a percutaneous PFO closure so an open surgical repair was performed with complete resolution of symptoms. We discuss the pathophysiology and management of platypnoea orthodeoxia syndrome.
一名80岁女性出现进行性呼吸困难，坐立或站立时加重，平卧时缓解。随后的检查发现卵圆孔未闭（PFO），有右向左的血流穿过房间隔（IAS）。诊断为继发于房间隔分流的平卧呼吸-直立性低氧血症综合征。技术因素排除了经皮封堵PFO的可能性，因此进行了开放性手术修复，症状完全缓解。我们讨论了平卧呼吸-直立性低氧血症综合征的病理生理学和治疗方法。
