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本文引用的文献

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Safety and Efficacy of Durvalumab (MEDI4736), an Anti-Programmed Cell Death Ligand-1 Immune Checkpoint Inhibitor, in Patients With Advanced Urothelial Bladder Cancer.抗程序性细胞死亡配体-1免疫检查点抑制剂度伐利尤单抗(MEDI4736)在晚期尿路上皮膀胱癌患者中的安全性和有效性
J Clin Oncol. 2016 Sep 10;34(26):3119-25. doi: 10.1200/JCO.2016.67.9761. Epub 2016 Jun 6.
2
Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial.阿替利珠单抗用于接受铂类化疗后病情进展的局部晚期和转移性尿路上皮癌患者:一项单臂、多中心、2期试验。
Lancet. 2016 May 7;387(10031):1909-20. doi: 10.1016/S0140-6736(16)00561-4. Epub 2016 Mar 4.
3
Effectiveness of Adjuvant Chemotherapy for Locally Advanced Bladder Cancer.局部晚期膀胱癌辅助化疗的疗效。
J Clin Oncol. 2016 Mar 10;34(8):825-32. doi: 10.1200/JCO.2015.64.1076. Epub 2016 Jan 19.
4
Cancer statistics, 2016.癌症统计数据,2016 年。
CA Cancer J Clin. 2016 Jan-Feb;66(1):7-30. doi: 10.3322/caac.21332. Epub 2016 Jan 7.
5
A Prognostic Gene Expression Signature in the Molecular Classification of Chemotherapy-naïve Urothelial Cancer is Predictive of Clinical Outcomes from Neoadjuvant Chemotherapy: A Phase 2 Trial of Dose-dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin with Bevacizumab in Urothelial Cancer.初治尿路上皮癌分子分类中的预后基因表达特征可预测新辅助化疗的临床结局:一项尿路上皮癌剂量密集型甲氨蝶呤、长春碱、阿霉素和顺铂联合贝伐单抗的2期试验
Eur Urol. 2016 May;69(5):855-62. doi: 10.1016/j.eururo.2015.08.034. Epub 2015 Sep 3.
6
Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung Cancer.纳武单抗与多西他赛治疗晚期鳞状细胞非小细胞肺癌的疗效比较
N Engl J Med. 2015 Jul 9;373(2):123-35. doi: 10.1056/NEJMoa1504627. Epub 2015 May 31.
7
PD-1 Blockade in Tumors with Mismatch-Repair Deficiency.错配修复缺陷肿瘤中的程序性死亡受体-1阻断
N Engl J Med. 2015 Jun 25;372(26):2509-20. doi: 10.1056/NEJMoa1500596. Epub 2015 May 30.
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Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma.纳武利尤单抗与伊匹木单抗联合用药或单药治疗初治黑色素瘤
N Engl J Med. 2015 Jul 2;373(1):23-34. doi: 10.1056/NEJMoa1504030. Epub 2015 May 31.
9
Nivolumab and ipilimumab versus ipilimumab in untreated melanoma.纳武利尤单抗与伊匹木单抗联合治疗对比伊匹木单抗单药治疗未经治疗的黑色素瘤
N Engl J Med. 2015 May 21;372(21):2006-17. doi: 10.1056/NEJMoa1414428. Epub 2015 Apr 20.
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Pembrolizumab for the treatment of non-small-cell lung cancer.帕博利珠单抗治疗非小细胞肺癌。
N Engl J Med. 2015 May 21;372(21):2018-28. doi: 10.1056/NEJMoa1501824. Epub 2015 Apr 19.

美国国立综合癌症网络(NCCN)指南解读:膀胱癌,2016年第2版

NCCN Guidelines Insights: Bladder Cancer, Version 2.2016.

作者信息

Clark Peter E, Spiess Philippe E, Agarwal Neeraj, Bangs Rick, Boorjian Stephen A, Buyyounouski Mark K, Efstathiou Jason A, Flaig Thomas W, Friedlander Terence, Greenberg Richard E, Guru Khurshid A, Hahn Noah, Herr Harry W, Hoimes Christopher, Inman Brant A, Kader A Karim, Kibel Adam S, Kuzel Timothy M, Lele Subodh M, Meeks Joshua J, Michalski Jeff, Montgomery Jeffrey S, Pagliaro Lance C, Pal Sumanta K, Patterson Anthony, Petrylak Daniel, Plimack Elizabeth R, Pohar Kamal S, Porter Michael P, Sexton Wade J, Siefker-Radtke Arlene O, Sonpavde Guru, Tward Jonathan, Wile Geoffrey, Dwyer Mary A, Smith Courtney

机构信息

From Vanderbilt-Ingram Cancer Center; Moffitt Cancer Center; Huntsman Cancer Institute at the University of Utah; Patient Advocate; Mayo Clinic Cancer Center; Stanford Cancer Institute; Massachusetts General Hospital Cancer Center; University of Colorado Cancer Center; UCSF Helen Diller Family Comprehensive Cancer Center; Fox Chase Cancer Center; Roswell Park Cancer Institute; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; Memorial Sloan Kettering Cancer Center; Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute; Duke Cancer Institute; UC San Diego Moores Cancer Center; Dana-Farber/Brigham and Women's Cancer Center; Robert H. Lurie Comprehensive Cancer Center of Northwestern University; Fred & Pamela Buffett Cancer Center; Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine; University of Michigan Comprehensive Cancer Center; City of Hope Comprehensive Cancer Center; St. Jude Children's Research Hospital/The University of Tennessee Health Science Center; Yale Cancer Center/Smilow Cancer Hospital; The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute; University of Washington/Seattle Cancer Care Alliance; The University of Texas MD Anderson Cancer Center; University of Alabama at Birmingham Comprehensive Cancer Center; and National Comprehensive Cancer Network.

出版信息

J Natl Compr Canc Netw. 2016 Oct;14(10):1213-1224. doi: 10.6004/jnccn.2016.0131.

DOI:10.6004/jnccn.2016.0131
PMID:
27697976
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5379654/
Abstract

These NCCN Guidelines Insights discuss the major recent updates to the NCCN Guidelines for Bladder Cancer based on the review of the evidence in conjunction with the expert opinion of the panel. Recent updates include (1) refining the recommendation of intravesical bacillus Calmette-Guérin, (2) strengthening the recommendations for perioperative systemic chemotherapy, and (3) incorporating immunotherapy into second-line therapy for locally advanced or metastatic disease. These NCCN Guidelines Insights further discuss factors that affect integration of these recommendations into clinical practice.

摘要

这些美国国立综合癌症网络(NCCN)指南见解基于证据审查并结合专家组的专家意见,讨论了NCCN膀胱癌指南近期的主要更新内容。近期更新包括:(1)完善卡介苗膀胱内灌注的推荐;(2)强化围手术期全身化疗的推荐;(3)将免疫疗法纳入局部晚期或转移性疾病的二线治疗。这些NCCN指南见解进一步讨论了影响将这些推荐纳入临床实践的因素。