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痴呆风险降低研究的未来:障碍与解决方案。

The future of dementia risk reduction research: barriers and solutions.

机构信息

Alzheimer's Research UK, Granta Park, Cambridge CB21 6AD, UK.

出版信息

J Public Health (Oxf). 2017 Dec 1;39(4):e275-e281. doi: 10.1093/pubmed/fdw103.

Abstract

BACKGROUND

We examine why dementia prevention and risk reduction are relatively underfunded and suggest potential remediation strategies. The paper is aimed at researchers, funders and policy-makers, both within dementia and also the wider health prevention field.

METHODS

A discussion-led workshop, attended by 58 academics, clinicians, funders and policy-makers.

RESULTS

The key barriers identified were the gaps in understanding the basic science of dementia; the complex interplay between individual risk factors; variations in study methodology; disincentives to collaboration; a lack of research capacity and leadership and the broader stigma of the condition. Recommendations were made to encourage strategic leadership, provide greater support for grant applications, promote collaboration and support randomized control trials for the research field.

CONCLUSION

Having identified the barriers, the key challenge is how to implement the potential solutions. This will require engagement with decision-makers within funding, policy and research to ensure that action takes place.

摘要

背景

我们探讨了为何预防痴呆症和降低风险的相关措施资金投入相对较少,并提出了一些潜在的补救策略。本文面向痴呆症领域以及更广泛的健康预防领域的研究人员、资助者和政策制定者。

方法

一场由 58 名学者、临床医生、资助者和政策制定者参加的以讨论为主导的研讨会。

结果

确定的主要障碍包括对痴呆症基础科学理解的差距;个体风险因素之间的复杂相互作用;研究方法的差异;合作的激励不足;研究能力和领导力的缺乏以及该病症的普遍污名化。建议鼓励战略领导力,为资助申请提供更多支持,促进合作,并为研究领域提供随机对照试验。

结论

在确定了障碍之后,关键的挑战是如何实施潜在的解决方案。这将需要与资金、政策和研究领域的决策者进行接触,以确保采取行动。

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