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Probe alignment and design issues of microelectromechanical system based optical coherence tomography endoscopic imaging.基于微机电系统的光学相干断层扫描内窥成像的探头对准与设计问题
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基于倾斜微机电系统(MEMS)镜的光学相干断层扫描内窥探头

Optical coherence tomography endoscopic probe based on a tilted MEMS mirror.

作者信息

Duan Can, Tanguy Quentin, Pozzi Antonio, Xie Huikai

机构信息

Department of Electrical and Computer Engineering, University of Florida, Gainesville, FL, 32611, USA;

Department of Electrical and Computer Engineering, University of Florida, Gainesville, FL, 32611, USA; Department of Micro Nano Science and Systems, FEMTO-ST, Besançon, 25000, France.

出版信息

Biomed Opt Express. 2016 Aug 10;7(9):3345-3354. doi: 10.1364/BOE.7.003345. eCollection 2016 Sep 1.

DOI:10.1364/BOE.7.003345
PMID:27699103
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5030015/
Abstract

This paper reports a compact microendoscopic OCT probe with an outer diameter of only 2.7 mm. The small diameter is enabled by a novel 2-axis scanning MEMS mirror with a preset 45° tilted angle. The tilted MEMS mirror is directly integrated on a silicon optical bench (SiOB). The SiOB provides mechanical support and electrical wiring to the mirror plate via a set of bimorph flexure, enabling a compact probe mount design without the requirement of a 45° slope, which is capable to dramatically reduce the probe size and ease the assembly process. Additionally, the SiOB also provides trenches with properly-designed opening widths for automatic alignment of the MEMS mirror, GRIN lens and optical fiber. The 45°-tilted MEMS mirror plate is actuated by four electrothermal bimorph actuators. The packaged 2.7 mm-diameter probe offers 2-axis side-view optical scanning with a large optical scan range of 40° at a low drive voltage of 5.5 Vdc in both axes, allowing a lateral scan area of 2.2 mm × 2.2 mm at a 3 mm working distance. High-resolution 2D and 3D OCT images of the IR card, imaging of meniscus specimens and rat brain slices, imaging of the human finger and nail have been obtained with a TDOCT system.

摘要

本文报道了一种外径仅为2.7毫米的紧凑型微型内窥光学相干断层扫描(OCT)探头。其小直径得益于一种新型的双轴扫描微机电系统(MEMS)镜,该镜具有预设的45°倾斜角。倾斜的MEMS镜直接集成在硅光学平台(SiOB)上。SiOB通过一组双压电晶片挠曲为镜板提供机械支撑和电气布线,从而实现紧凑的探头安装设计,无需45°斜坡,这能够显著减小探头尺寸并简化组装过程。此外,SiOB还提供具有适当设计开口宽度的沟槽,用于MEMS镜、梯度折射率(GRIN)透镜和光纤的自动对准。45°倾斜的MEMS镜板由四个电热双压电晶片致动器驱动。封装后的2.7毫米直径探头在两个轴上以5.5 Vdc的低驱动电压提供双轴侧视光学扫描,光学扫描范围大,为40°,在3毫米工作距离处允许横向扫描面积为2.2毫米×2.2毫米。使用时域光学相干断层扫描(TDOCT)系统已获得红外卡的高分辨率二维和三维OCT图像、半月板标本和大鼠脑切片的成像、人手指和指甲的成像。