Kim Ki Hean, Park B Hyle, Maguluri Gopi N, Lee Tom W, Rogomentich Fran J, Bancu Mirela G, Bouma Brett E, de Boer Johannes F, Bernstein Jonathan J
Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA 02114 USA.
Opt Express. 2007 Dec 24;15(26):18130-40. doi: 10.1364/oe.15.018130.
A two-axis scanning catheter was developed for 3D endoscopic imaging with spectral domain optical coherence tomography (SD-OCT). The catheter incorporates a micro-mirror scanner implemented with microelectromechanical systems (MEMS) technology: the micro-mirror is mounted on a two-axis gimbal comprised of folded flexure hinges and is actuated by magnetic field. The scanner can run either statically in both axes or at the resonant frequency (>= 350Hz) for the fast axis. The assembled catheter has an outer diameter of 2.8 mm and a rigid part of 12 mm in length. Its scanning range is +/- 20 in optical angle in both axes with low voltages (1 approximately 3V), resulting in a scannable length of approximately 1 mm at the surface in both axes, even with the small catheter size. The catheter was incorporated with a multi-functional SD-OCT system for 3D endoscopic imaging. Both intensity and polarization-sensitive images could be acquired simultaneously at 18.5K axial scans/s. In vivo 3D images of human fingertips and oral cavity tissue are presented as a demonstration.
我们开发了一种用于三维内镜成像的双轴扫描导管，该成像采用谱域光学相干断层扫描（SD-OCT）技术。该导管集成了一个采用微机电系统（MEMS）技术实现的微镜扫描仪：微镜安装在一个由折叠挠性铰链组成的双轴万向架上，并由磁场驱动。扫描仪可以在两个轴上静态运行，也可以在快轴上以共振频率（≥350Hz）运行。组装后的导管外径为2.8毫米，刚性部分长度为12毫米。在低电压（1至3V）下，其在两个轴上的光学角度扫描范围均为±20°，即使导管尺寸较小，在表面两个轴上的可扫描长度也约为1毫米。该导管与一个用于三维内镜成像的多功能SD-OCT系统相结合。强度图像和偏振敏感图像都可以在每秒18.5K次轴向扫描的速度下同时获取。作为演示，展示了人体指尖和口腔组织的体内三维图像。
