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基于几何精确模型的时间分辨漫射光学光谱技术用于体参数恢复。

Time resolved diffuse optical spectroscopy with geometrically accurate models for bulk parameter recovery.

作者信息

Guggenheim James A, Bargigia Ilaria, Farina Andrea, Pifferi Antonio, Dehghani Hamid

机构信息

PSIBS Doctoral Training Centre, University of Birmingham, Birmingham, UK; Department of Medical Physics and Biomedical Engineering, University College London, London, UK.

Center for Nano-Science and Technology @POLIMI, Istituto Italiano di Tecnologia, Milano, Italy.

出版信息

Biomed Opt Express. 2016 Aug 31;7(9):3784-3794. doi: 10.1364/BOE.7.003784. eCollection 2016 Sep 1.

Abstract

A novel straightforward, accessible and efficient approach is presented for performing hyperspectral time-domain diffuse optical spectroscopy to determine the optical properties of samples accurately using geometry specific models. To allow bulk parameter recovery from measured spectra, a set of libraries based on a numerical model of the domain being investigated is developed as opposed to the conventional approach of using an analytical semi-infinite slab approximation, which is known and shown to introduce boundary effects. Results demonstrate that the method improves the accuracy of derived spectrally varying optical properties over the use of the semi-infinite approximation.

摘要

本文提出了一种新颖、直接、可及且高效的方法,用于执行高光谱时域漫射光学光谱分析,以使用特定几何模型准确测定样品的光学特性。为了从测量光谱中恢复体参数,与使用解析半无限平板近似的传统方法相反,开发了一组基于所研究区域数值模型的库,已知并表明传统方法会引入边界效应。结果表明,与使用半无限近似相比,该方法提高了导出的光谱变化光学特性的准确性。

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