Politecnico di Milano, Dipartimento di Fisica, Piazza Leonardo da Vinci 32, 20133 Milano, Italy.
Appl Spectrosc. 2012 Aug;66(8):944-50. doi: 10.1366/11-06461. Epub 2012 Jul 13.
We present a new compact system for time-domain diffuse optical spectroscopy of highly scattering media operating in the wavelength range from 1100 nm to 1700 nm. So far, this technique has been exploited mostly up to 1100 nm: we extended the spectral range by means of a pulsed supercontinuum light source at a high repetition rate, a prism to spectrally disperse the radiation, and a time-gated InGaAs/InP single-photon avalanche diode working up to 1700 nm. A time-correlated single-photon counting board was used as processing electronics. The system is characterized by linear behavior up to absorption values of about 3.4 cm(-1) where the relative error is 17%. A first measurement performed on lipids is presented: the absorption spectrum shows three major peaks at 1200 nm, 1400 nm, and 1700 nm.
我们提出了一种新的紧凑系统,用于在 1100nm 至 1700nm 的波长范围内对高散射介质进行时域漫反射光学光谱学研究。到目前为止,这项技术主要在 1100nm 以下得到了应用:我们通过使用高重复率的脉冲超连续光源、棱镜来进行光谱色散以及工作在 1700nm 的时间门控 InGaAs/InP 单光子雪崩二极管来扩展光谱范围。一个时间相关的单光子计数板被用作处理电子设备。该系统的特点是在吸收值约为 3.4cm(-1)时呈线性行为,相对误差为 17%。我们展示了在脂质上进行的第一次测量:吸收光谱在 1200nm、1400nm 和 1700nm 处呈现出三个主要峰值。