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对金、滑石和铁燧岩开采职业流行病学研究中与细长矿物颗粒(EMP)暴露相关的死亡率的综述。

A review of mortality associated with elongate mineral particle (EMP) exposure in occupational epidemiology studies of gold, talc, and taconite mining.

作者信息

Mandel Jeffrey H, Alexander Bruce H, Ramachandran Gurumurthy

机构信息

Division of Environmental Health Sciences, University of Minnesota School of Public Health, Minneapolis, Minnesota.

出版信息

Am J Ind Med. 2016 Dec;59(12):1047-1060. doi: 10.1002/ajim.22641. Epub 2016 Oct 4.

Abstract

BACKGROUND

Mining of gold, taconite, and talc may involve exposure to elongate mineral particles (EMP). The involved EMPs are typically non-asbestiform, include dimensions that regulatory definitions exclude, and have been less studied.

METHODS

A review of the literature was undertaken for this exposure and occupational epidemiological studies that occur in gold, talc, and taconite mining.

RESULTS

Quantitative EMP exposure information in these industries is incomplete. However, there are consistent findings of pneumoconiosis in each of these types of mining. A recent case-control study suggests a possible association between this exposure and mesothelioma. Lung cancer is inconsistently reported in these industries and is an unlikely outcome of non-asbestiform EMP exposure. There is evidence of cardiovascular mortality excess across all of these types of mining.

CONCLUSIONS

Non-malignant respiratory disease and cardiovascular mortality have been consistently increased in these industries. Further investigation, including additional insights for the role of non-asbestiform EMP, is warranted. Am. J. Ind. Med. 59:1047-1060, 2016. © 2016 Wiley Periodicals, Inc.

摘要

背景

金矿、铁燧岩矿和滑石矿的开采可能涉及接触细长矿物颗粒(EMP)。所涉及的EMP通常是非石棉状的,包括监管定义所排除的尺寸,并且研究较少。

方法

对金矿、滑石矿和铁燧岩矿开采中发生的这种接触及职业流行病学研究进行了文献综述。

结果

这些行业中EMP接触的定量信息不完整。然而,在每种类型的采矿中都有尘肺病的一致发现。最近的一项病例对照研究表明这种接触与间皮瘤之间可能存在关联。这些行业中肺癌的报告不一致,并且非石棉状EMP接触不太可能导致肺癌。有证据表明所有这些类型的采矿中都存在心血管疾病死亡率过高的情况。

结论

这些行业中非恶性呼吸道疾病和心血管疾病死亡率持续上升。有必要进行进一步调查,包括对非石棉状EMP作用的更多见解。《美国工业医学杂志》59:1047 - 1060,2016年。© 2016威利期刊公司。

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