Marković-Glamocak M
Lijec Vjesn. 1989 Apr-May;111(4-5):150-3.
The immunocytochemical method with monoclonal antibodies for estrogen receptors has been presented. This method has been adjusted for fine needle aspirates of the breast carcinoma tissue. The procedure of collecting, fixating, staining of aspirates and interpreting of our first results was described. Estrogen receptors were determined in 19 cytologic samples of the breast carcinoma. In more than a half of the investigated samples (11/19), the results were negative, whereas only a smaller number (8/19) provided positive results. The results were compared with those obtained using a quantitative biochemical method which was employed in investigating of tumor tissue. The value of this method compared with the sofar known methods has been discussed.
本文介绍了用单克隆抗体检测雌激素受体的免疫细胞化学方法。该方法已针对乳腺癌组织的细针穿刺抽吸物进行了调整。描述了抽吸物的收集、固定、染色过程以及对我们首批结果的解读。在19份乳腺癌细胞学样本中检测了雌激素受体。在超过一半的被调查样本(11/19)中,结果为阴性,而只有少数样本(8/19)呈阳性。将这些结果与使用定量生化方法检测肿瘤组织所获得的结果进行了比较。讨论了该方法与目前已知方法相比的价值。