Pavlov A S, Datsenko V S
Med Radiol (Mosk). 1989 Aug;34(8):27-31.
A many-year-old study of 3680 breast cancer patients receiving different types of radiation therapy as part of combined or multimodality treatment led to the following conclusions. Surgical intervention used alone or the first stage of combined treatment was found appropriate for stage I only. The most preferable modality in all cases was preoperative irradiation provided in large fractional regimens for operable tumors and, when possible, in combination with UHF-therapy; the use of common fractions with the incorporation of a primary focus and all zones of regional metastatic spreading in the zone of radiation exposure was found appropriate for inoperable tumors.
一项针对3680名乳腺癌患者的多年研究表明，这些患者接受了不同类型的放射治疗作为联合或多模式治疗的一部分，得出了以下结论。单独使用手术干预或联合治疗的第一阶段仅适用于I期患者。在所有情况下，最优选的治疗方式是对可手术肿瘤采用大分割方案进行术前照射，并在可能的情况下与超高频治疗联合使用；对于不可手术肿瘤，采用包含原发灶和放射野内区域转移扩散的所有区域的常规分割照射被认为是合适的。
